Rollin Bernard E
Department of Philosophy, Colorado State University, Fort Collins, CO 80523, USA.
Animals (Basel). 2020 Sep 19;10(9):1695. doi: 10.3390/ani10091695.
There are three sorts of issues associated with genetic engineering and, by implication, with xenotransplantation. These are dangers associated with the technology, animal welfare issues, and the claim that genetic engineering represents a technology that humans should not embark upon. Using the hearts of pigs for humans in need of transplants has been a major issue in xenotransplantation. There are dangers associated with such use, such as immunological rejection of the organ, endogenous viruses infecting the recipients, and issues of privacy. In addition, the issue of fair distribution of organs arises. Animal welfare issues also arise, most notably the living conditions of the donor animals, issues notably present in confinement agriculture. A major issue emerges from animals' being kept under conditions that fail to meet the needs dictated by the animals' biological and psychological natures. Xenotransplantation animals will be kept under deprived laboratory conditions that similarly fail to meet the animals' natures. This is a significant concern for society in general. There are also issues of "bad ethics" arising from scientists' disavowal of ethical concerns in science. This in turn, coupled with societal ignorance of science, creates a climate for proliferation of religious and other non-rational concerns, such as the claim that xenotransplantation violates God's will. These spurious concerns can only be ameliorated when public understanding of science improves, and scientific understanding of ethics increases.
与基因工程相关,进而与异种移植相关的问题有三类。这些是与该技术相关的危险、动物福利问题,以及认为基因工程是一项人类不应涉足的技术的观点。将猪的心脏用于有移植需求的人类一直是异种移植中的一个主要问题。这种使用存在一些危险,比如器官的免疫排斥、感染接受者的内源性病毒以及隐私问题。此外,还出现了器官公平分配的问题。动物福利问题也随之产生,最显著的是供体动物的生活条件问题,这在圈养农业中尤为突出。一个主要问题源于动物被饲养在无法满足其生物学和心理本性所决定需求的条件下。异种移植动物将被饲养在同样无法满足其本性的匮乏实验室条件下。这总体上是社会的一个重大关切。科学家对科学中的伦理问题不予理会还引发了“不良伦理”问题。这反过来,再加上社会对科学的无知,营造了一种宗教及其他非理性担忧扩散的氛围,比如声称异种移植违背上帝意志。只有当公众对科学的理解得到提升,且科学对伦理的理解有所增加时,这些虚假的担忧才能得到缓解。