Zhang Na, Du Songming, Tang Zhenchuang, Zheng Mengqi, Ma Guansheng
Department of Nutrition and Food Hygiene, School of Public Health, Peking University; 38 Xue Yuan Road, Hai Dian District, Beijing 100191, China.
Laboratory of Toxicological Research and Risk Assessment for Food Safety, Peking University; 38 Xue Yuan Road, Hai Dian District, Beijing 100191, China.
Int J Environ Res Public Health. 2017 Aug 27;14(9):966. doi: 10.3390/ijerph14090966.
: Water accounts for about 75% of brain mass. Cognitive performances and mood may be impaired by hypohydration and improved by water supplementation. Two surveys conducted in China demonstrated that a large proportion of adults and children drank less fluid than the amounts recommended by the Chinese Nutrition Society. The association between hypohydration and cognitive performance has not been reported in China. The purpose of this study is to explore the effect of water supplementation on cognitive performances and mood among male college students in Cangzhou, China. : A randomized controlled trial is designed to test the hypothesis. A total of 68 male college students aged 18-25 years will be recruited and randomly assigned into water-supplementation group (WS group, = 34) and no water-supplementation group (NW group, = 34) after an overnight fasting, i.e., without eating foods and drinking fluid for 12 h. The first morning urine will be collected to determine urine osmolality on the water supplementation day. Cognitive performances and mood will be performed before water supplementation by researchers with questionnaire. Subjects in the WS group will drink 400 mL purified water within 5 min, while those in NW group will not drink any fluid. One hour later, urine will be collected and urine osmolality, cognitive performances and mood will be measured again. Mixed model of repeated measures ANOVA will be used to investigate the effect of water supplementation on cognitive performances. The study would provide information about the benefit of water supplementation on cognitive performances. : The study protocol is reviewed and approved by the Ethical Review Committee of the Chinese Nutrition Society. Ethical approval project identification code is CNS-2015-001. Results will be published according to the CONSORT statement and will be reported in peer-reviewed journals. : Chinese clinical trial registry. Identifier: ChiCTR-IOR-15007020. Registry name "The effect of hydration on cognitive performance".
水占大脑质量的约75%。水合不足可能会损害认知能力和情绪，而补充水分则可改善这些情况。在中国进行的两项调查表明，很大一部分成年人和儿童的饮水量低于中国营养学会推荐的量。在中国，水合不足与认知能力之间的关联尚未见报道。本研究的目的是探讨在中国沧州，补充水分对男性大学生认知能力和情绪的影响。：设计一项随机对照试验来检验该假设。总共将招募68名年龄在18至25岁的男性大学生，在禁食过夜（即12小时不进食和饮水）后，随机分为补水组（WS组，n = 34）和不补水组（NW组，n = 34）。在补水日收集晨尿以测定尿渗透压。研究人员在补水前通过问卷对认知能力和情绪进行评估。WS组的受试者将在5分钟内饮用400毫升纯净水，而NW组的受试者不饮用任何液体。1小时后，收集尿液并再次测量尿渗透压、认知能力和情绪。将使用重复测量方差分析的混合模型来研究补水对认知能力的影响。该研究将提供有关补水对认知能力益处的信息。：该研究方案已由中国营养学会伦理审查委员会审查并批准。伦理批准项目识别码为CNS - 2015 - 001。结果将根据CONSORT声明发表，并将在同行评审期刊上报告。：中国临床试验注册中心。标识符：ChiCTR - IOR - 15007020。注册名称“水合作用对认知能力的影响”
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