Zenebe Tizazu, Mitiku Meseret, Alem Yonas
Department of Medicine, Medical Microbiology Unit, DebreBerhan University, DebreBerhan, Ethiopia.
Department of Medical Laboratory Sciences, MaddaWalabu University, Bale Robe, Ethiopia.
Int J Microbiol. 2020 Sep 7;2020:8844294. doi: 10.1155/2020/8844294. eCollection 2020.
Diarrhea remains as a high health burden, especially to children in low-income countries including Ethiopia. Diarrheagenic have been commonly associated as bacterial pathogens causing diarrheal disease among children. This systemic review and meta-analysis was intended to determine the pooled prevalence of in under-five children with diarrhea in Ethiopia. A comprehensive search in PubMed, Google Scholar, ScienceDirect, ResearchGate, and Google search engine and manual searching were done for this systematic review and meta-analysis. The eligibility criteria for selecting studies were studies involving under-five children with diarrhea in Ethiopia, published articles, cross-sectional studies, and articles reported in English. The study was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) checklist. The data analysis was done using STATA 16.0 software. Cochran's -test and statistics were used for the assessment of heterogeneity. The random-effect model was used to estimate the pooled prevalence of . A total of 797 articles were initially retrieved, and finally, 11 studies met the eligibility criteria and were included in the final meta-analysis. The pooled prevalence of was 25% (95% CI: 9, 41). The pooled prevalence was varied by region, detection method, and sample size. The high prevalence emphasizes that is a potential pathogen in under-five children with diarrhea in Ethiopia.
腹泻仍然是一个严重的健康负担，尤其是对包括埃塞俄比亚在内的低收入国家的儿童。致泻性[病原体名称未给出]通常被认为是导致儿童腹泻疾病的细菌病原体。本系统评价和荟萃分析旨在确定埃塞俄比亚五岁以下腹泻儿童中[病原体名称未给出]的合并患病率。为此项系统评价和荟萃分析，在PubMed、谷歌学术、ScienceDirect、ResearchGate和谷歌搜索引擎中进行了全面检索，并进行了手工检索。选择研究的纳入标准为涉及埃塞俄比亚五岁以下腹泻儿童的研究、已发表的文章、横断面研究以及用英文报道的文章。该研究是根据系统评价和荟萃分析的首选报告项目（PRISMA）清单进行的。数据分析使用STATAA TA 16.0软件。采用 Cochr an's Q检验和I²统计量评估异质性。采用随机效应模型估计[病原体名称未给出]的合并患病率。最初共检索到797篇文章，最终有11项研究符合纳入标准并被纳入最终的荟萃分析。[病原体名称未给出]的合并患病率为25%（95%置信区间：9%，41%）。合并患病率因地区、检测方法和样本量而异。高患病率强调[病原体名称未给出]是埃塞俄比亚五岁以下腹泻儿童中的一种潜在病原体。
