Kerns Aileen, Ross Andrew, Sugihara Eric M, Bathula Samba Siva
Department of Otolaryngology-Head and Neck Surgery, Detroit Medical Center, Detroit, USA.
Department of Otolaryngology-Head and Neck Surgery, Detroit Medical Center/Michigan State University, Detroit, USA.
Cureus. 2020 Sep 16;12(9):e10496. doi: 10.7759/cureus.10496.
Lymphoepithelial carcinoma (LEC) is a variant of anaplastic carcinoma usually found in the nasopharynx. It is a rare, aggressive malignant tumor in the salivary glands, which is usually associated with Epstein-Barr virus (EBV), and often presents with facial nerve paralysis when in the parotid gland. This case report is unique in that our patient had EBV-negative LEC, with facial nerve involvement and a concurrent primary papillary thyroid carcinoma (PTC). We successfully managed this patient with surgery and adjuvant chemoradiotherapy. The patient has responded well to the treatment and she showed no evidence of disease at the 24-month follow-up.
淋巴上皮癌（LEC）是间变性癌的一种变体，通常见于鼻咽部。它是唾液腺中一种罕见的侵袭性恶性肿瘤，通常与爱泼斯坦-巴尔病毒（EBV）相关，在腮腺时常常伴有面神经麻痹。本病例报告的独特之处在于，我们的患者患有EBV阴性的LEC，伴有面神经受累且同时患有原发性乳头状甲状腺癌（PTC）。我们通过手术及辅助放化疗成功治疗了该患者。患者对治疗反应良好，在24个月的随访中未发现疾病迹象。
