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具有淋巴上皮特征且与爱泼斯坦-巴尔病毒(EBV)无关的甲状腺乳头状癌:1例罕见病例

Papillary Thyroid Carcinoma With Lymphoepithelial Features and Lacking Association With Epstein-Barr Virus (EBV): A Rare Case.

作者信息

Bendari Ahmed, Geetha Saroja Devi, Al-Refai Reham, Zhong Xuelin, Sham Sunder, Harshan Manju

机构信息

Department of Pathology, Lenox Hill Hospital, New York, USA.

Department of Pathology, Zucker School of Medicine, North Shore University Hospital/Long Island Jewish Medical Center, Northwell Health, Greenvale, USA.

出版信息

Cureus. 2024 Feb 29;16(2):e55222. doi: 10.7759/cureus.55222. eCollection 2024 Feb.

DOI:10.7759/cureus.55222
PMID:38558705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10981357/
Abstract

Papillary thyroid carcinoma (PTC) is the most common primary thyroid malignancy. PTC is diagnosed based on its hallmark nuclear characteristics, but a myriad of histological variants has been identified some of which can be diagnostically challenging due to its rarity and overlapping histomorphology with other entities. We report a rare variant of PTC with lymphoepithelial features which lacked association with Epstein-Barr Virus (EBV). In such cases, a thorough workup to rule out metastasis from other sites should be undertaken.

摘要

甲状腺乳头状癌(PTC)是最常见的原发性甲状腺恶性肿瘤。PTC是根据其标志性核特征进行诊断的,但已发现了无数种组织学变体,其中一些由于其罕见性以及与其他实体的组织形态学重叠,在诊断上具有挑战性。我们报告了一种具有淋巴上皮特征的罕见PTC变体,其与爱泼斯坦-巴尔病毒(EBV)无关。在这种情况下,应进行全面检查以排除其他部位的转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9408/10981357/8f30c874d508/cureus-0016-00000055222-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9408/10981357/0ed67e47bfbd/cureus-0016-00000055222-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9408/10981357/2f86530b50ee/cureus-0016-00000055222-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9408/10981357/8f30c874d508/cureus-0016-00000055222-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9408/10981357/0ed67e47bfbd/cureus-0016-00000055222-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9408/10981357/2f86530b50ee/cureus-0016-00000055222-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9408/10981357/8f30c874d508/cureus-0016-00000055222-i03.jpg

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Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach.2022 年世界卫生组织甲状腺肿瘤分类更新:一种标准化诊断方法。
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