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益生菌临床试验的全球分析数据。

Data on global analysis of clinical trials with probiotics.

作者信息

Dronkers Theresia M G, Ouwehand Arthur C, Rijkers Ger T

机构信息

Department of Sciences, University College Roosevelt, Lange Noordstraat 1, 4331 CB Middelburg, the Netherlands.

DuPont Nutrition and Biosciences, Danisco Sweeteners Oy. Global Health and Nutrition Sciences, Sokeritehtaantie 20, Kantvik 02460, Finland.

出版信息

Data Brief. 2020 Sep 3;32:106269. doi: 10.1016/j.dib.2020.106269. eCollection 2020 Oct.

Abstract

Data on characteristics of clinical trials with probiotics, registered at ClinicalTrials.gov were retrieved from the registry . Data on the registration process itself (moment of registration of the trial in relation to date of inclusion of first participant, data of completion of the study) as well as the number of participants were analysed. A trend analysis (over the period 2000-2020) was made of the number of participants in clinical trials with probiotics on gastrointestinal conditions and diseases. A comparison was made between conditions and diseases studied in completed clinical trials with those trials not yet recruiting participants. The data can be used and reused for assessment of the quality of clinical studies with probiotics and to identify future trends in applications of probiotics.

摘要

从ClinicalTrials.gov注册库中检索了有关益生菌临床试验特征的数据。分析了注册过程本身的数据(试验注册时间与第一名参与者纳入日期的关系、研究完成日期)以及参与者数量。对2000年至2020年期间胃肠道疾病益生菌临床试验的参与者数量进行了趋势分析。对已完成临床试验中研究的病症与尚未招募参与者的试验进行了比较。这些数据可用于评估益生菌临床研究的质量,并确定益生菌应用的未来趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a1f/7490816/746049966eea/gr1.jpg

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