Retina Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ocul Immunol Inflamm. 2022 Apr 3;30(3):697-702. doi: 10.1080/09273948.2020.1823424. Epub 2020 Sep 23.
To demonstrate the value of "smoothness index (SI)" as a novel tool for quantitative analysis of iris surface findings in unilateral Fuchs' uveitis (FU).
Both phakic eyes from patients with unilateral FU as well as healthy control subjects underwent anterior segment optical coherence tomography (AS-OCT). The ImageJ software was used for calculating the SI.
Forty eyes from 20 patients with unilateral FU and 40 eyes from 20 healthy subjects were enrolled. In FU eyes, mean overall SI (0.876 ± 0.030) was significantly higher than fellow control eyes (0.841 ± 0.041) ( = .001). Mean inter-eye difference for overall SI in the FU patients (0.037 ± 0.030) was significantly larger than the healthy control subjects (0.018 ± 0.014) ( = .033).
Iris "smoothness index" can be used to quantitatively assess iris surface smoothness and may facilitate the diagnosis of subtle iris atrophic changes in eyes affected by FU especially in the absence of heterochromia.
展示“平滑指数（SI）”作为一种定量分析单侧 Fuchs 葡萄膜炎（FU）虹膜表面发现的新工具的价值。
对单侧 FU 患者的未行晶状体摘除眼以及健康对照者的眼前节光学相干断层扫描（AS-OCT）图像进行分析。使用 ImageJ 软件计算 SI。
共纳入 20 例单侧 FU 患者的 40 只眼和 20 名健康对照者的 40 只眼。FU 眼中，总 SI（0.876±0.030）均值显著高于对侧正常眼（0.841±0.041）（=0.001）。FU 患者双眼间总 SI 的差值（0.037±0.030）明显大于健康对照组（0.018±0.014）（=0.033）。
虹膜“平滑指数”可用于定量评估虹膜表面的平滑度，有助于诊断 FU 受累眼的细微虹膜萎缩性改变，尤其是在无虹膜异色的情况下。
