Lakshmanan Seetha, Malik Amer
Internal Medicine, Roger Williams Medical Center, Providence, USA.
Gastroenterology, Roger Williams Medical Center, Providence, USA.
Cureus. 2020 Aug 20;12(8):e9886. doi: 10.7759/cureus.9886.
The novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused a global health crisis. This virus uses angiotensin converting enzyme 2 (ACE2) receptors to facilitate cellular entry. ACE2 receptors appear to be highly expressed in pancreatic exocrine glands and islet cells, more so than in lung tissues, suggesting that pancreatic injury can occur despite having only mild COVID-19 symptoms. We report a patient with COVID-19 who presented with only gastrointestinal symptoms and discuss the importance of identifying pancreatitis early to improve prognosis.
由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的2019年新型冠状病毒病（COVID-19）已引发全球健康危机。这种病毒利用血管紧张素转换酶2（ACE2）受体促进细胞进入。ACE2受体似乎在胰腺外分泌腺和胰岛细胞中高度表达，比在肺组织中表达得更高，这表明即使只有轻微的COVID-19症状也可能发生胰腺损伤。我们报告了一名仅表现出胃肠道症状的COVID-19患者，并讨论了早期识别胰腺炎以改善预后的重要性。
