Department of Virology, Faculty of Veterinary Medicine, University of Sadat City, Sadat, 32897, Egypt.
Department of Virology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Virus Genes. 2020 Dec;56(6):705-711. doi: 10.1007/s11262-020-01793-x. Epub 2020 Sep 24.
Recently, multiple spillover events between domesticated poultry and wild birds have been reported for several avian viruses. This phenomenon highlights the importance of the livestock-wildlife interface in the possible emergence of novel viruses. The aim of the current study was to investigate the potential spillover and epidemiological links of infectious bursal disease virus (IBDV) between wild birds and domestic poultry. To this end, twenty-eight cloacal swabs were collected from four species of free-living Egyptian wild birds (i.e. mallard duck, bean goose, white-fronted goose and black-billed magpie). Genetic and phylogenetic analysis of three positive isolates revealed that the IBDV/USC-1/2019 strain clustered with previously reported very virulent IBDV (vvIBDV) Egyptian isolates. Interestingly, two other wild bird-origin isolates (i.e. IBDV/USC-2/2019 and IBDV/USC-3/2019) grouped with a vaccine strain that is being used in commercial poultry. In conclusion, our results revealed the molecular detection of vaccine and vvIBDV-like strains in Egyptian wild birds and highlighted the potential role of wild birds in IBDV epidemiology in disease-endemic regions.
最近，有报道称几种禽病毒在驯化家禽和野生鸟类之间发生了多次溢出事件。这种现象突出了牲畜-野生动物界面在新病毒可能出现方面的重要性。本研究旨在调查传染性法氏囊病病毒（IBDV）在野生鸟类和家禽之间的潜在溢出和流行病学联系。为此，从 4 种自由生活的埃及野生鸟类（即绿头鸭、斑头雁、白额雁和黑嘴喜鹊）中采集了 28 个泄殖腔拭子。对三个阳性分离株的遗传和系统发育分析表明，IBDV/USC-1/2019 株与先前报道的高致病性传染性法氏囊病病毒（vvIBDV）埃及分离株聚集在一起。有趣的是，另外两个野生鸟类起源的分离株（即 IBDV/USC-2/2019 和 IBDV/USC-3/2019）与一种正在商业家禽中使用的疫苗株聚集在一起。总之，我们的研究结果揭示了埃及野生鸟类中疫苗和 vvIBDV 样株的分子检测，并强调了野生鸟类在疾病流行地区 IBDV 流行病学中的潜在作用。
