Rahman Asma, Niloofa Roshan, De Zoysa Ishan M, Cooray Akila D, Kariyawasam Jayani, Seneviratne Suranjith L
Department of Surgery, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Department of Zoology and Environment Sciences, Faculty of Science, University of Colombo, Colombo, Sri Lanka.
SAGE Open Med. 2020 Sep 10;8:2050312120957925. doi: 10.1177/2050312120957925. eCollection 2020.
COVID-19, a respiratory viral infection, has affected more than 10 million individuals worldwide. Common symptoms include fever, dry cough, fatigue and shortness of breath. Some patients show neurological manifestations such as headache, dizziness, cerebrovascular disease, peripheral nerve and muscle symptoms and smell and taste impairment. In previous studies, SARS-CoV-1 and MERS-CoV were found to affect the nervous system. Given the high similarity between SARS-CoV-1 and SARS-CoV-2, effects on the nervous system by SARS-CoV-2 are a possibility. We have outlined the common neurological manifestations in COVID-19 (information are up-to-date as of June 2020) and discussed the possible pathogenetic mechanisms and management options.
新型冠状病毒肺炎（COVID-19）是一种呼吸道病毒感染疾病，已在全球范围内影响了超过1000万人。常见症状包括发热、干咳、乏力和呼吸急促。一些患者出现神经学表现，如头痛、头晕、脑血管疾病、周围神经和肌肉症状以及嗅觉和味觉障碍。在先前的研究中，发现严重急性呼吸综合征冠状病毒1型（SARS-CoV-1）和中东呼吸综合征冠状病毒（MERS-CoV）会影响神经系统。鉴于SARS-CoV-1与严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）高度相似，SARS-CoV-2有可能对神经系统产生影响。我们概述了COVID-19中常见的神经学表现（信息截至2020年6月），并讨论了可能的发病机制和管理方案。
