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苯并噻唑烷催化合成的最新进展。

Recent Advances in Catalytic Synthesis of Benzosultams.

机构信息

Key Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education & Hubei Key Laboratory of Catalysis and Materials Science, School of Chemistry and Materials Science, South-Central University for Nationalities, Wuhan 430074, China.

出版信息

Molecules. 2020 Sep 23;25(19):4367. doi: 10.3390/molecules25194367.

Abstract

Benzosultams represent one category of multi-heteroatom heterocyclic scaffolds, which have been frequently found in pharmaceuticals, agricultural agents, and chiral catalysts. Given the diversely significant functions of these compounds in organic and medicinal chemistry, great efforts have been made to develop novel catalytic systems for the efficient construction of benzosultam motifs over the past decades. Herein, in this review, we mainly summarize the recent advances in the field of catalytic synthesis of benzosultams from 2017 to August of 2020, with an emphasis on the scopes and mechanisms of representative reactions.

摘要

苯并噻唑代表多杂原子杂环支架的一类,广泛存在于药物、农用化学品和手性催化剂中。鉴于这些化合物在有机和药物化学中具有多样化的重要功能,过去几十年来,人们致力于开发新型催化体系以高效构建苯并噻唑结构。在此,我们主要综述了 2017 年至 2020 年 8 月间苯并噻唑催化合成方面的最新进展,重点讨论了代表性反应的适用范围和反应机理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c281/7582503/dc329bd19657/molecules-25-04367-sch001.jpg

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