Institute of Bio- und Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, 52425 Jülich, Germany.
Viruses. 2020 Sep 23;12(10):1065. doi: 10.3390/v12101065.
are well-known antibiotic producers, also characterized by a complex morphological differentiation. , like all bacteria, are confronted with the constant threat of phage predation, which in turn shapes bacterial evolution. However, despite significant sequencing efforts recently, relatively few phages infecting have been characterized compared to other genera. Here, we present the isolation and characterization of five novel phages. All five phages belong to the family, based on their morphology as determined by transmission electron microscopy. Genome sequencing and life style predictions suggested that four of them were temperate phages, while one had a lytic lifestyle. Moreover, one of the newly sequenced phages shows very little homology to already described phages, highlighting the still largely untapped viral diversity. Altogether, this study expands the number of characterized phages of and sheds light on phage evolution and phage-host dynamics in .
是众所周知的抗生素产生菌,也具有复杂的形态分化特征。与所有细菌一样,它们面临着噬菌体捕食的持续威胁,而噬菌体捕食反过来又塑造了细菌的进化。然而,尽管最近进行了大量测序工作,但与其他属相比,感染 的噬菌体相对较少。在这里,我们介绍了五个新的 噬菌体的分离和特性。根据透射电子显微镜确定的形态,所有五个噬菌体都属于 科。基因组测序和生活方式预测表明,其中四个是温和噬菌体,而一个是裂解性噬菌体。此外,新测序的一个噬菌体与已经描述的噬菌体几乎没有同源性,突出了仍有很大一部分未开发的病毒多样性。总的来说,这项研究扩展了 噬菌体的数量,并揭示了 在噬菌体进化和噬菌体-宿主动态中的作用。