Cutillo A G, Morris A H, Ailion D C, Durney C H, Case T A
J Thorac Imaging. 1986 Jul;1(3):39-51. doi: 10.1097/00005382-198607000-00007.
NMR imaging techniques are applicable to the assessment of lung water content and distribution because the NMR signal is, under certain conditions, proportional to tissue proton density. NMR imaging is noninvasive, easily repeatable, free from ionizing radiation, and particularly suitable for the assessment of spatial lung water distribution. Lung water content and distribution have been estimated in excised animal lungs and in intact dead or living animals, under normal conditions and in various types of experimental pulmonary edema. Excised human lungs and human subjects have also been studied. Published data indicate that measurements of lung water content by NMR imaging techniques are feasible. These techniques estimate lung water spatial distribution with satisfactory accuracy and excellent resolving power. The application of NMR imaging techniques poses several problems and limitations, but available data suggest that most of the problems can be solved. NMR imaging has the potential to become a powerful tool for lung water research. Prospects of clinical application are also encouraging; numerous applications can be foreseen, although lack of mobility of NMR imaging systems may be a significant limitation in critical care medicine.
核磁共振成像技术可用于评估肺含水量及其分布情况，因为在某些条件下，核磁共振信号与组织质子密度成正比。核磁共振成像具有非侵入性、易于重复、无电离辐射的特点，尤其适用于评估肺水的空间分布。在正常条件下以及各种类型的实验性肺水肿中，已对切除的动物肺以及完整的死体或活体动物的肺含水量及其分布进行了评估。也对切除的人体肺和人体受试者进行了研究。已发表的数据表明，通过核磁共振成像技术测量肺含水量是可行的。这些技术能够以令人满意的准确性和出色的分辨能力估计肺水的空间分布。核磁共振成像技术的应用存在一些问题和局限性，但现有数据表明大多数问题是可以解决的。核磁共振成像有潜力成为肺水研究的有力工具。临床应用前景也很乐观；尽管在重症监护医学中，核磁共振成像系统缺乏移动性可能是一个重大限制，但仍可预见众多应用。
