Cutillo A G, Morris A H, Ailion D C, Durney C H, Ganesan K
Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah Medical Center, Salt Lake City 84132.
J Thorac Imaging. 1988 Jul;3(3):51-8. doi: 10.1097/00005382-198807000-00012.
Considerable progress has been made in the application of nuclear magnetic resonance (NMR) imaging and nonimaging techniques to the quantitative assessment of pulmonary edema. NMR measurements offer the advantages of being noninvasive, relatively rapid, and easily repeatable. In addition, NMR imaging is suitable for the determination of lung water distribution. Studies of various animal models have shown that NMR techniques can adequately detect and quantify relative changes in lung water content and distribution in various types of experimental lung injury. Preliminary observations in humans suggest that NMR measurement of relative lung water changes in clinical pulmonary edema should be feasible. Although the application of NMR to the assessment of pulmonary edema appears to be very promising, it also poses significant problems that must be solved before it can be established as a standard experimental and clinical method.
在将核磁共振(NMR)成像和非成像技术应用于肺水肿的定量评估方面已经取得了相当大的进展。NMR测量具有非侵入性、相对快速且易于重复的优点。此外,NMR成像适用于确定肺水分布。对各种动物模型的研究表明,NMR技术能够充分检测和量化各种类型实验性肺损伤中肺水含量和分布的相对变化。对人类的初步观察表明,NMR测量临床肺水肿中肺水的相对变化应该是可行的。尽管NMR在肺水肿评估中的应用似乎非常有前景,但在它能够成为一种标准的实验和临床方法之前,还存在一些必须解决的重大问题。