Tyan Kevin, Levin Adriane, Avalos-Pacheco Alejandra, Plana Deborah, Rand Eleanor A, Yang Helen, Maliszewski Laura E, Chylek Lily A, Atta Lyla, Tye Mark A, Carmack Mary M, Oglesby N Synclaire, Burgin Susan, Yu Sherry H, LeBoeuf Nicole R, Kemp Jacqueline M
Greater Boston Pandemic Fabrication Team (PanFab) c/o Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, Massachusetts, USA.
Harvard Medical School, Boston, Massachusetts, USA.
Open Forum Infect Dis. 2020 Aug 31;7(9):ofaa396. doi: 10.1093/ofid/ofaa396. eCollection 2020 Sep.
Proper disinfection using adequate disinfecting agents will be necessary for infection control strategies against coronavirus disease 2019 (COVID-19). However, limited guidance exists on effective surface disinfectants or best practices for their use against severe acute respiratory coronavirus 2. We outlined a process of fully characterizing over 350 products on the Environmental Protection Agency List N, including pH, method of delivery, indication for equipment sterilization, and purchase availability. We then developed a streamlined set of guidelines to help rapidly evaluate and select suitable disinfectants from List N, including practicality, efficacy, safety, and cost/availability. This resource guides the evaluation of ideal disinfectants amidst practical considerations posed by the COVID-19 pandemic.
使用适当的消毒剂进行正确消毒对于针对2019冠状病毒病(COVID-19)的感染控制策略至关重要。然而,关于有效的表面消毒剂或针对严重急性呼吸综合征冠状病毒2使用它们的最佳做法的指导有限。我们概述了一个对美国环境保护局N类清单上350多种产品进行全面表征的过程,包括pH值、递送方法、设备灭菌指示和购买可用性。然后,我们制定了一套简化的指南,以帮助从N类清单中快速评估和选择合适的消毒剂,包括实用性、有效性、安全性以及成本/可用性。该资源在COVID-19大流行带来的实际考虑因素中指导对理想消毒剂的评估。