Federal Research Center Krasnoyarsk Science Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia.
Research Institute of Medical Problems of the North, Krasnoyarsk, Russia.
Bull Exp Biol Med. 2020 Sep;169(5):683-686. doi: 10.1007/s10517-020-04954-y. Epub 2020 Sep 29.
We studied the effectiveness of using magnetic ferrihydrite nanoparticles of bacterial origin carrying ampicillin for local treatment of burn wounds in rats using a magnetic field. It was found that the use of these nanoparticles in combination with a magnetic field accelerated wound healing and reduced the titer of microorganisms in comparison with the corresponding parameters in the untreated animals and animals treated with nanoparticles or ampicillin alone.
我们研究了利用具有氨苄青霉素负载能力的细菌源性磁性水铁矿纳米颗粒,并通过磁场对大鼠烧伤创面进行局部治疗的效果。结果发现,与未处理动物以及单独使用纳米颗粒或氨苄青霉素处理的动物相比,这些纳米颗粒联合磁场的使用可加速创面愈合,并降低微生物滴度。