Research Group Microbiology & Systems Biology, Netherlands Organization for Applied Scientific Research (TNO), 3704HE Zeist, The Netherlands.
Nutrients. 2020 Sep 25;12(10):2945. doi: 10.3390/nu12102945.
Health claims on foods are a way of informing consumers about the health benefits of a food product. Traditionally, these claims are based on scientific evaluation of markers originating from a pharmacological view on health. About a decade ago, the definition of health has been rephrased to 'the ability to adapt' that opened up the possibility for a next generation of health claims based on a new way of quantifying health by evaluating resilience. Here, we would like to introduce an opportunity for future scientific substantiation of health claims on food products by using whole-grain wheat as an example. Characterization of the individual whole wheat grain food product or whole wheat flour would probably be considered as sufficiently characterized by the European Food Safety Authority, while the food category whole grain is not specific enough. Meta-analysis provides the scientific evidence that long-term whole-grain wheat consumption is beneficial for health, although results from single 'gold standard' efficacy studies are not always straight forward based on classic measurement methods. Future studies may want to underpin the scientific argumentation that long-term whole grain wheat consumption improves resilience, by evaluating the disruption and rate of a selected panel of blood markers in response to a standardized oral protein glucose lipid tolerance test and aggregated into biomarkers with substantiated physiological benefits, to make a next-generation health claim for whole-grain wheat achievable in the near future.
食品声称是一种向消费者告知食品有益健康的方式。传统上，这些声称是基于对源自药理学健康观的标志物进行科学评估的。大约十年前，健康的定义被重新表述为“适应能力”，这为基于评估弹性的新一代健康声称开辟了可能性。在这里，我们想以全麦小麦为例，为未来对食品声称进行科学证实提供一个机会。欧洲食品安全局可能认为单个全麦谷物食品产品或全麦面粉的特征已经足够具体，而整个谷物食品类别则不够具体。荟萃分析提供了科学证据，表明长期食用全麦小麦有益于健康，尽管基于经典测量方法，单个“黄金标准”功效研究的结果并不总是直接的。未来的研究可能希望通过评估对标准化口服蛋白质葡萄糖脂质耐量试验的反应的选定血液标志物面板的中断和速率，并将其聚合到具有证实的生理益处的生物标志物中，来支持长期全谷物小麦消费可提高适应能力的科学论点，从而在不久的将来为全谷物小麦提出新一代健康声称。
