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埃塞俄比亚五岁以下儿童疟疾的决定因素:贝叶斯多层分析。

Determinants of malaria among under-five children in Ethiopia: Bayesian multilevel analysis.

机构信息

Department of Public Health, College of Medicine and Health Sciences, Samara University, Samara, Ethiopia.

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

出版信息

BMC Public Health. 2020 Sep 29;20(1):1468. doi: 10.1186/s12889-020-09560-1.

DOI:10.1186/s12889-020-09560-1
PMID:32993550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7526346/
Abstract

BACKGROUND

In Ethiopia, malaria is one of the public health problems, and it is still among the ten top leading causes of morbidity and mortality among under-five children. However, the studies conducted in the country have been inconclusive and inconsistent. Thus, this study aimed to assess factors associated with malaria among under-five children in Ethiopia.

METHODS

We retrieved secondary data from the malaria indicator survey data collected from September 30 to December 10, 2015, in Ethiopia. A total of 8301 under-five-year-old children who had microscopy test results were included in the study. Bayesian multilevel logistic regression models were fitted and Markov chain Monte Carlo simulation was used to estimate the model parameters using Gibbs sampling. Adjusted Odd Ratio with 95% credible interval in the multivariable model was used to select variables that have a significant association with malaria.

RESULTS

In this study, sleeping under the insecticide-treated bed nets during bed time (ITN) [AOR 0.58,95% CI, 0.31-0.97)], having 2 and more ITN for the household [AOR 0.43, (95% CI, 0.17-0.88)], have radio [AOR 0.41, (95% CI, 0.19-0.78)], have television [AOR 0.19, (95% CI, 0.01-0.89)] and altitude [AOR 0.05, (95% CI, 0.01-0.13)] were the predictors of malaria among under-five children.

CONCLUSIONS

The study revealed that sleeping under ITN, having two and more ITN for the household, altitude, availability of radio, and television were the predictors of malaria among under-five children in Ethiopia. Thus, the government should strengthen the availability and utilization of ITN to halt under-five mortality due to malaria.

摘要

背景

在埃塞俄比亚,疟疾是公共卫生问题之一,它仍然是导致五岁以下儿童发病率和死亡率的十大原因之一。然而,该国进行的研究结果并不明确且不一致。因此,本研究旨在评估与埃塞俄比亚五岁以下儿童疟疾相关的因素。

方法

我们从 2015 年 9 月 30 日至 12 月 10 日收集的疟疾指标调查数据中检索到二次数据。共有 8301 名接受过显微镜检查结果的五岁以下儿童纳入本研究。使用贝叶斯多水平逻辑回归模型进行拟合,并使用 Gibbs 抽样进行马尔可夫链蒙特卡罗模拟来估计模型参数。多变量模型中调整后的优势比(95%可信区间)用于选择与疟疾有显著关联的变量。

结果

在这项研究中,睡觉时使用经杀虫剂处理的蚊帐(ITN)[调整后的优势比(AOR)0.58,95%可信区间(CI)0.31-0.97)]、家庭拥有 2 个或更多 ITN [AOR 0.43,(95% CI,0.17-0.88)]、拥有收音机[AOR 0.41,(95% CI,0.19-0.78)]、拥有电视[AOR 0.19,(95% CI,0.01-0.89)]和海拔高度[AOR 0.05,(95% CI,0.01-0.13)]是五岁以下儿童疟疾的预测因素。

结论

本研究表明,在埃塞俄比亚,使用 ITN 睡觉、家庭拥有 2 个或更多 ITN、海拔高度、收音机和电视的可用性是五岁以下儿童疟疾的预测因素。因此,政府应加强 ITN 的供应和利用,以阻止因疟疾导致的五岁以下儿童死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/1b70b8c22526/12889_2020_9560_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/b258a6acc2a0/12889_2020_9560_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/351f12b150a8/12889_2020_9560_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/749dfb4de8bb/12889_2020_9560_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/4f405ad302e1/12889_2020_9560_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/1b70b8c22526/12889_2020_9560_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/b258a6acc2a0/12889_2020_9560_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/351f12b150a8/12889_2020_9560_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/749dfb4de8bb/12889_2020_9560_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/4f405ad302e1/12889_2020_9560_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f11/7526346/1b70b8c22526/12889_2020_9560_Fig5_HTML.jpg

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