Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA
Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.
Vet Rec. 2020 Dec 19;187(12):489. doi: 10.1136/vr.106046. Epub 2020 Sep 29.
Noise aversion is a common behavioural disorder in dogs; affected dogs show fear behaviours in response to noise stimuli. Pharmacological treatment is effective for many dogs; clinical reports suggest anxiolytic treatment lowers the need for treatment over time. We aimed to evaluate the effect of dexmedetomidine oromucosal gel for dogs with noise aversion over a series of noise events. Furthermore, we evaluated burden of care for owners of dogs with noise aversion via questionnaire.
Owners of enrolled dogs completed records for 10 noise events indicating whether their dog received dexmedetomidine gel and pretreatment and post-treatment anxiety scores; adverse events were noted. Owners were queried about burden of care.
Twenty-two client-owned dogs completed recordings for 10 events. Logistic regression results showed a significant effect for time of event with decreased probability of receiving treatment for subsequent events (OR=0.75, P=0.0017). Within an event, significant improvement in anxiety was seen (median improvement 11 points; paired Wilcoxon; P<0.0001). We found overall burden of care was manageable, yet many owners agreed with statements regarding frustration (42 per cent), stress (46 per cent), guilt (42 per cent) and sadness (75 per cent) about their dog's condition.
Repeated use of dexmedetomidine gel for noise events resulted in decreased need for administration. Burden of care is important to discuss with clients.
对噪音的反感是犬的一种常见行为障碍；受影响的犬在听到噪音刺激时会表现出恐惧行为。药物治疗对许多犬有效；临床报告表明，随着时间的推移，使用抗焦虑药物治疗会降低治疗的需求。我们的目的是评估在一系列噪声事件中，右美托咪定口腔凝胶对患有噪声恐惧症的犬的治疗效果。此外，我们通过问卷调查评估了患有噪声恐惧症犬的主人的护理负担。
接受治疗的犬的主人完成了 10 次噪声事件的记录，记录包括他们的犬是否接受了右美托咪定凝胶治疗、治疗前和治疗后的焦虑评分；并记录了不良反应。主人还被询问了护理负担的问题。
22 只宠物犬完成了 10 次事件的记录。逻辑回归结果显示，事件时间对接受治疗的可能性有显著影响，后续事件接受治疗的可能性降低（OR=0.75，P=0.0017）。在一次事件中，犬的焦虑明显改善（中位数改善 11 分；配对 Wilcoxon；P<0.0001）。我们发现整体护理负担是可以管理的，但许多主人对他们的犬的状况表示认同，认为有挫败感（42%）、压力（46%）、内疚（42%）和悲伤（75%）。
重复使用右美托咪定凝胶治疗噪声事件会降低治疗的需求。护理负担是需要与客户讨论的重要问题。
