Kwiek Bartłomiej, Sieczych Julia, Rożalski Michał, Kowalewski Cezary, Ambroziak Marcin
Department of Dermatology and Immunodermatology, Medical University of Warsaw, Warsaw, Poland.
Department of Dermatology and Venereology, Medical University of Warsaw, Warsaw, Poland.
Postepy Dermatol Alergol. 2020 Aug;37(4):572-578. doi: 10.5114/ada.2019.83520. Epub 2020 Mar 11.
New devices such as the large spot KTP laser are being introduced for the treatment of port-wine stains (PWS).
To assess the efficacy of the large spot 532 nm laser for non-facial PWS with 3D image analysis and compare it with subjective evaluation.
Twenty PWS were photographed with a 3D photo unit before and after 532 nm large spot KTP laser treatment. Fifteen lesions were previously treated by different devices and five were not. Objective analysis of percentage improvement based on a 3D digital assessment of combined color and area improvement was performed and rates of improvement were determined as well as subjective evaluation of before and after images by a physician on a 5-grade scale.
Mean objective response was 57.0%. A poor response was observed in 5% with the objective method and with no patient with the subjective method. A moderate response was achieved by 25% and 30% with the objective and subjective assessment respectively. A significant response was obtained by 55% objectively and 10% subjectively. 75-100% was achieved by 15% and 60% in the objective and subjective analysis respectively. The two methods significantly correlated with each other but the average subjective improvement rates were higher than the objective rates.
Both objective and subjective analysis indicated that the large spot 532 nm laser is highly effective in the treatment of the neck and trunk. 3D color and area objective analysis provides an accurate tool to measure the efficacy of PWS treatment.
诸如大光斑KTP激光等新型设备正被引入用于治疗葡萄酒色斑（PWS）。
通过三维图像分析评估大光斑532nm激光治疗非面部葡萄酒色斑的疗效，并与主观评估进行比较。
用三维照相设备在532nm大光斑KTP激光治疗前后对20例葡萄酒色斑进行拍照。其中15个皮损此前曾用不同设备治疗过，5个未曾治疗过。基于对颜色和面积改善的三维数字评估进行客观的改善百分比分析，确定改善率，并由一名医生对治疗前后图像进行5级主观评估。
平均客观反应率为57.0%。客观评估方法显示5%反应较差，主观评估方法无患者反应较差。客观和主观评估分别有25%和30%达到中度反应。客观评估有55%获得显著反应，主观评估有10%获得显著反应。客观和主观分析分别有15%和60%达到75%-100%的改善。两种方法显著相关，但主观平均改善率高于客观改善率。
客观和主观分析均表明，大光斑532nm激光治疗颈部和躯干葡萄酒色斑疗效显著。三维颜色和面积客观分析为测量葡萄酒色斑治疗疗效提供了一种准确的工具。
