1Swiss Tropical and Public Health Institute, Basel, Switzerland.
2University of Basel, Basel, Switzerland.
Am J Trop Med Hyg. 2020 Dec;103(6):2260-2267. doi: 10.4269/ajtmh.20-0252. Epub 2020 Sep 24.
We estimated the financial costs of different interventions against urogenital schistosomiasis, implemented by the Zanzibar Elimination of Schistosomiasis Transmission (ZEST) project, on Pemba and Unguja islands, Tanzania. We used available data on project activities, resources used, and costs reported in the accounting information systems of ZEST partners. The costs were estimated for all the activities related to snail control, behavior change interventions, the impact assessment surveys, and management of the whole program. Costs are presented in US$ for the full duration of the ZEST project from 2011/2012 to 2017. The total financial costs of implementing snail control activities over 5 years, excluding the costs for donated Bayluscide, were US$55,796 on Pemba and US$73,581 on Unguja, mainly driven by personnel costs. The total financial costs of implementing behavior change activities were US$109,165 on Pemba and US$155,828 on Unguja, with costs for personnel accounting for 47% on Pemba and 69% on Unguja. Costs of implementing biannual mass drug administration refer to the estimated 2.4 million treatments provided on Pemba over 4 years (2013-2016), and do not include the costs of donated praziquantel. The total cost per provided treatment was, on average, US$0.21. This study showed the value of exploiting administrative data to estimate costs of major global health interventions. It also provides an evidence base for financial costs and main cost drivers of implementing multiple combinations of intervention sets that inform decisions regarding the feasibility and affordability of implementing schistosomiasis control and elimination strategies.
我们估算了坦桑尼亚奔巴岛和温古贾岛实施的桑给巴尔消灭血吸虫病传播项目（ZEST）中针对尿路血吸虫病的不同干预措施的财务成本。我们使用了项目活动、资源使用和 ZEST 合作伙伴会计信息系统中报告的成本的现有数据。这些成本是针对与螺类控制、行为改变干预措施、影响评估调查以及整个项目管理相关的所有活动进行估算的。这些成本以美元表示，涵盖了 ZEST 项目从 2011/2012 年至 2017 年的全部持续时间。5 年内实施螺类控制活动的总财务成本（不包括捐赠的贝鲁西库德费用），在奔巴为 55796 美元，在温古贾为 73581 美元，主要由人员成本驱动。实施行为改变活动的总财务成本，在奔巴为 109165 美元，在温古贾为 155828 美元，人员成本分别占奔巴的 47%和温古贾的 69%。实施两年一次的大规模药物治疗的成本是指在 4 年（2013-2016 年）期间在奔巴提供的估计 240 万例治疗，不包括捐赠的吡喹酮成本。每次提供治疗的平均成本为 0.21 美元。本研究展示了利用行政数据估算主要全球卫生干预措施成本的价值。它还为实施多种干预措施组合的财务成本和主要成本驱动因素提供了证据基础，为实施血吸虫病控制和消除策略的可行性和可负担性决策提供了信息。
