Department of Internal Medicine University Hospital Motol, Second Faculty of Medicine, Charles University, V Úvalu 84, 150 00 Prague, Czech Republic.
Arbeitsgemeinschaft der Belegärzte am Alice-Hospital, 64287 Darmstadt, Germany.
Diabetes Res Clin Pract. 2020 Dec;170:108470. doi: 10.1016/j.diabres.2020.108470. Epub 2020 Sep 28.
The aim of this study is to establish the prevalence of diabetes (DM) and prediabetes in the Czech population aged 25-64 years and to evaluate the relationships with various cardiometabolic, sociodemographic, and lifestyle risk factors.
This was an epidemiological study with a stratified, crosssectional, random sampling design. Sociodemographic, lifestyle, and anamnestic data were collected through interviewer-administered questionnaires, medical examination, and biochemical assays.
Among the 1189 participants, 114 were diagnosed with DM (9.6%), 330 with prediabetes (27.8%) and 745 were non-diabetes/non-prediabetes individuals (62.7%). Logistic regression analysis showed that overweight, general and abdominal obesity, hypertension, and lower level of HDL (increased risk) significantly increased the risk of both prediabetes and DM, while living in the cities diminished risk of DM. Among lifestyle variables the significant increased risk of prediabetes and DM was found for smokers and ex-smokers. In other lifestyle variables (marijuana lifetime prevalence, physical activity and frequency of alcohol drinking) the significantly higher or lower risk for prediabetes or DM was not found.
The study shows a high prevalence of DM and prediabetes in the Czech population of age between 25 and 64, providing data on their association with several risk factors.
本研究旨在确定 25-64 岁捷克人群中糖尿病（DM）和糖尿病前期的患病率，并评估其与各种心血管代谢、社会人口学和生活方式危险因素的关系。
这是一项采用分层、横断面、随机抽样设计的流行病学研究。通过面访式问卷调查、体格检查和生化检测收集社会人口学、生活方式和既往病史数据。
在 1189 名参与者中，114 人被诊断为 DM（9.6%），330 人患有糖尿病前期（27.8%），745 人是非糖尿病/非糖尿病前期个体（62.7%）。逻辑回归分析显示，超重、普通和腹部肥胖、高血压以及较低水平的高密度脂蛋白（增加风险）显著增加了糖尿病前期和 DM 的风险，而生活在城市则降低了 DM 的风险。在生活方式变量中，吸烟者和曾经吸烟者患糖尿病前期和 DM 的风险显著增加。在其他生活方式变量（大麻终生患病率、身体活动和饮酒频率）中，未发现糖尿病前期或 DM 的风险显著更高或更低。
该研究表明，25-64 岁捷克人群中 DM 和糖尿病前期的患病率较高，为这些疾病与多种危险因素的关系提供了数据。
