Bone Infection Unit, Department Orthopaedic and Traumatology 2, Santa Corona Hospital, Pietra Ligure (SV), Italy.
Department of Surgical Sciences (DISC), Orthopaedic Clinic, Ospedale Policlinico San Martino, Genova, Italy.
PLoS One. 2020 Oct 1;15(10):e0239981. doi: 10.1371/journal.pone.0239981. eCollection 2020.
Few studies provide an analysis of conservative two-stage revision of hip periprosthetic joint infection (PJI) and its impact on final outcome. A conservative revision is defined when soft tissues and bone quality enable the use of primary prosthetic components. Data of patients treated for chronic hip PJI who underwent two-stage revision between 2009 and 2016 and had a minimum of 2 years of follow-up were collected. Oxford Hip Score (OHS), Harris Hip Score (HHS) and radiological and microbiological data were retrieved and analysed. Clinical and functional outcome, survival, mortality, eradication, reinfection and re-revision rates within subgroups of patients with primary components and revision components are reported herein. A total of 148 patients underwent two-stage hip exchange with a mean follow-up of 55.6 ± 23.1 months and a mean age at surgery of 64.3 ± 12.7 years. Forty-four percent of patients underwent conservative revision. The mean HHS significantly improved from 40.6 ± 9.4 points to the final value of 87.8 ± 10.5 points (p = .002), and the mean OHS went from 20.3 ± 3.8 points to 40.3 ± 5. points (p< .001). Patients who were treated with primary components or isolated revision stems in the second stage had a significant reduction in surgical times (p< .001). The mortality rate for all causes of death was 6.8%, the eradication rate was 89.9%, the reinfection rate was 4.7% and the reoperation rate was 7.4% without differences between conservative and non-conservative revisions. Two-stage exchange arthroplasty for total hip arthroplasty (THA) PJI is a good strategy that provides satisfactory results, high eradication rates and no further need for revision. The conservative two-stage revision in patients with adequate bone stock represents a feasible option with good results and survival rates.
很少有研究对髋关节假体周围关节感染(PJI)的保守性两期翻修及其对最终结果的影响进行分析。当软组织和骨质量允许使用原始假体部件时,可定义为保守性翻修。收集了 2009 年至 2016 年间接受慢性髋关节 PJI 两期翻修且至少随访 2 年的患者的数据。回顾并分析了牛津髋关节评分(OHS)、Harris 髋关节评分(HHS)以及影像学和微生物学数据。报告了在此类患者中采用原始组件和翻修组件的亚组的临床和功能结果、存活率、死亡率、清除率、再感染率和再翻修率。共 148 例患者接受了两期髋关节置换术,平均随访 55.6 ± 23.1 个月,平均手术年龄 64.3 ± 12.7 岁。44%的患者接受了保守性翻修。HHS 平均值从 40.6 ± 9.4 分显著改善至最终的 87.8 ± 10.5 分(p =.002),OHS 平均值从 20.3 ± 3.8 分改善至 40.3 ± 5. 分(p<.001)。在第二期治疗中采用原始组件或单独翻修干骺端的患者手术时间显著缩短(p<.001)。所有原因导致的死亡率为 6.8%,清除率为 89.9%,再感染率为 4.7%,再手术率为 7.4%,保守性翻修和非保守性翻修之间无差异。对于全髋关节置换术(THA)PJI 的两期关节置换术是一种良好的策略,可提供满意的结果、高清除率且无需进一步翻修。对于具有足够骨量的患者,保守性两期翻修是一种可行的选择,可获得良好的结果和存活率。