Division of Endocrinology, Harold Schnitzer Diabetes Health Center, Oregon Health & Science University, Portland, OR 97239, USA.
Artificial Intelligence for Medical Systems Lab, Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR 97239, USA.
Biosensors (Basel). 2020 Sep 29;10(10):138. doi: 10.3390/bios10100138.
The accuracy of continuous glucose monitoring (CGM) sensors may be significantly impacted by exercise. We evaluated the impact of three different types of exercise on the accuracy of the Dexcom G6 sensor. Twenty-four adults with type 1 diabetes on multiple daily injections wore a G6 sensor. Participants were randomized to aerobic, resistance, or high intensity interval training (HIIT) exercise. Each participant completed two in-clinic 30-min exercise sessions. The sensors were applied on average 5.3 days prior to the in-clinic visits (range 0.6-9.9). Capillary blood glucose (CBG) measurements with a Contour Next meter were performed before and after exercise as well as every 10 min during exercise. No CGM calibrations were performed. The median absolute relative difference (MARD) and median relative difference (MRD) of the CGM as compared with the reference CBG did not differ significantly from the start of exercise to the end exercise across all exercise types (ranges for aerobic MARD: 8.9 to 13.9% and MRD: -6.4 to 0.5%, resistance MARD: 7.7 to 14.5% and MRD: -8.3 to -2.9%, HIIT MARD: 12.1 to 16.8% and MRD: -14.3 to -9.1%). The accuracy of the no-calibration Dexcom G6 CGM was not significantly impacted by aerobic, resistance, or HIIT exercise.
连续血糖监测 (CGM) 传感器的准确性可能会受到运动的显著影响。我们评估了三种不同类型的运动对 Dexcom G6 传感器准确性的影响。24 名接受多次每日注射的 1 型糖尿病成人佩戴了 G6 传感器。参与者被随机分配到有氧运动、抗阻运动或高强度间歇训练 (HIIT) 运动。每位参与者都完成了两次 30 分钟的门诊运动。传感器平均在门诊就诊前 5.3 天（范围 0.6-9.9）贴上。在运动前后以及运动期间每 10 分钟进行一次 Contour Next 血糖仪的毛细血管血糖 (CBG) 测量。未进行 CGM 校准。与参考 CBG 相比，CGM 的中位绝对相对差异 (MARD) 和中位相对差异 (MRD) 在所有运动类型中从运动开始到结束都没有显著差异（有氧运动 MARD 范围：8.9 至 13.9%和 MRD：-6.4 至 0.5%，抗阻运动 MARD：7.7 至 14.5%和 MRD：-8.3 至-2.9%，HIIT MARD：12.1 至 16.8%和 MRD：-14.3 至-9.1%）。未经校准的 Dexcom G6 CGM 的准确性不受有氧运动、抗阻运动或 HIIT 运动的显著影响。
