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子宫内膜异位症与生殖:我们的认识进展。

Endometriosis and Reproduction: What We Have Learned.

机构信息

The University of Edinburgh Medical School, Edinburgh, UK.

IVI Madrid, Rey Juan Carlos University, Madrid, Spain.

出版信息

Yale J Biol Med. 2020 Sep 30;93(4):571-577. eCollection 2020 Sep.

PMID:33005121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7513434/
Abstract

Endometriosis, despite only affecting 10-15% of women of fertile age, is still an enigmatic disease. Recent developments in assisted reproductive technology have contributed to a better understanding of where and how endometriosis could compromise fertility. In this mini-review we will show how the main point of damage in endometriosis is quantitative impairment of the ovaries, if the "less is more" mantra should be applied when considering ovarian surgery, and when fertility preservation prior to ovarian surgery could be considered. Endometrial receptivity, however, does not seem to be affected.

摘要

子宫内膜异位症虽然仅影响 10-15%的育龄妇女,但仍是一种神秘的疾病。辅助生殖技术的最新进展有助于更好地理解子宫内膜异位症如何以及在何处损害生育能力。在这个迷你综述中,我们将展示如果“少即是多”的口号适用于卵巢手术,以及在卵巢手术前何时可以考虑进行生育力保存,那么子宫内膜异位症的主要损害点在哪里。然而,子宫内膜容受性似乎不受影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7679/7513434/8d7e6780c475/yjbm_93_4_571_g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7679/7513434/8d7e6780c475/yjbm_93_4_571_g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7679/7513434/8d7e6780c475/yjbm_93_4_571_g01.jpg

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Endometriosis and Reproduction: What We Have Learned.子宫内膜异位症与生殖:我们的认识进展。
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本文引用的文献

1
Endometriosis.子宫内膜异位症
N Engl J Med. 2020 Mar 26;382(13):1244-1256. doi: 10.1056/NEJMra1810764.
2
The role of pharmacotherapy in the treatment of endometriosis across the lifespan.药物治疗在女性一生各阶段治疗子宫内膜异位症中的作用。
Expert Opin Pharmacother. 2020 Jun;21(8):893-903. doi: 10.1080/14656566.2020.1738386. Epub 2020 Mar 12.
3
Oocyte vitrification for fertility preservation in women with endometriosis: an observational study.内异症患者生育力保存的卵母细胞玻璃化冷冻:一项观察性研究。
Int J Womens Health. 2023 May 12;15:741-763. doi: 10.2147/IJWH.S404660. eCollection 2023.
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Fertility preservation in women with benign gynaecological conditions.患有良性妇科疾病女性的生育力保存
Hum Reprod Open. 2023 Apr 6;2023(2):hoad012. doi: 10.1093/hropen/hoad012. eCollection 2023.
5
Oocyte Cryopreservation in Patients with Endometriosis: Current Knowledge and Number Needed to Treat.子宫内膜异位症患者的卵母细胞冷冻保存:当前认知与治疗所需数量
J Clin Med. 2022 Aug 4;11(15):4559. doi: 10.3390/jcm11154559.
6
Long non-coding RNA DHRS4 antisense RNA 1 inhibits ectopic endometrial cell proliferation, migration, and invasion in endometriosis by regulating microRNA-139-5p expression.长非编码 RNA DHRS4 反义 RNA 1 通过调控 microRNA-139-5p 的表达抑制子宫内膜异位症中异位内膜细胞的增殖、迁移和侵袭。
Bioengineered. 2022 Apr;13(4):9792-9804. doi: 10.1080/21655979.2022.2060781.
7
Effect of Neiyi Prescription of QIU on autophagy and angiogenic ability of endometriosis via the PPARγ/NF-κB signaling pathway.内异方秋衣对子宫内膜异位症自噬及血管生成能力的影响通过 PPARγ/NF-κB 信号通路。
Arch Gynecol Obstet. 2022 Aug;306(2):533-545. doi: 10.1007/s00404-022-06537-w. Epub 2022 Apr 3.
8
Can Endometriosis-Related Oxidative Stress Pave the Way for New Treatment Targets?内异症相关氧化应激是否能为新的治疗靶点铺平道路?
Int J Mol Sci. 2021 Jul 1;22(13):7138. doi: 10.3390/ijms22137138.
Fertil Steril. 2020 Apr;113(4):836-844. doi: 10.1016/j.fertnstert.2019.11.017. Epub 2020 Mar 4.
4
Rethinking mechanisms, diagnosis and management of endometriosis.重新思考子宫内膜异位症的发病机制、诊断和治疗。
Nat Rev Endocrinol. 2019 Nov;15(11):666-682. doi: 10.1038/s41574-019-0245-z. Epub 2019 Sep 5.
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Single-cell RNA sequencing of oocytes from ovarian endometriosis patients reveals a differential transcriptomic profile associated with lower quality.对卵巢子宫内膜异位症患者卵母细胞的单细胞 RNA 测序揭示了与低质量相关的差异转录组谱。
Hum Reprod. 2019 Jul 8;34(7):1302-1312. doi: 10.1093/humrep/dez053.
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Gynaecologists' view on diagnostic delay and care performance in endometriosis in the Netherlands.荷兰妇科医生对子宫内膜异位症诊断延误和护理表现的看法。
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Endometrioma, fertility, and assisted reproductive treatments: connecting the dots.卵巢巧克力囊肿、生育能力与辅助生殖治疗:理清其中的关系。
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Fertil Steril. 2017 Jul;108(1):28-31. doi: 10.1016/j.fertnstert.2017.06.002.