饮酒。癌症的主要危险因素之一。

Alcohol consumption. A leading risk factor for cancer.

机构信息

WHO Collaboration Centre, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, ON, M5S 2S1, Canada; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, ON, M5S 2S1, Canada; Dalla Lana School of Public Health, University of Toronto, 155 College Street, 6th floor, Toronto, ON, M5T 3M7, Canada; Institute of Medical Science, University of Toronto, Faculty of Medicine, Medical Sciences Building, 1 King's College Circle, Room 2374, Toronto, ON, M5S 1A8, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, ON, M5S 2S1, Canada; Department of Psychiatry, University of Toronto, 250 College Street, 8th floor, Toronto, ON, M5T 1R8, Canada; Institute of Clinical Psychology and Psychotherapy & Center of Clinical Epidemiology and Longitudinal Studies (CELOS), Technische Universität Dresden, Chemnitzer Str. 46, 01187, Dresden, Germany.

出版信息

Chem Biol Interact. 2020 Nov 1;331:109280. doi: 10.1016/j.cbi.2020.109280. Epub 2020 Oct 1.

DOI:10.1016/j.cbi.2020.109280

PMID:33010221

Abstract

In 2016, alcohol consumption was one of the leading risk factors for cancer development and cancer death globally, causing an estimated 376 200 cancer deaths, representing 4.2% of all cancer deaths, and 10.3 million cancer disability-adjusted life years lost, representing 4.2% of all cancer disability-adjusted life years lost. The impact of alcohol consumption on cancer in 2016 varied by age group; the proportion of cancer deaths attributable to alcohol consumption ranged from 13.9% of cancer deaths among people aged 30-34 years to 2.7% of cancer deaths among people aged 80-84 years. The burden of cancers caused by alcohol consumption might be decreased through (i) individual-level and societal-level interventions that reduce alcohol consumption, and (ii) measures that target those risk factors that interact with alcohol consumption to increase the risk of cancer or that directly affect the risk of alcohol-related cancers.

摘要

2016 年，饮酒是全球癌症发展和癌症死亡的主要风险因素之一，导致约 376200 人死于癌症，占所有癌症死亡人数的 4.2%，并导致 1030 万人丧失癌症伤残调整生命年，占所有癌症伤残调整生命年损失的 4.2%。2016 年，酒精消费对癌症的影响因年龄组而异；归因于酒精消费的癌症死亡比例范围从 30-34 岁人群中 13.9%的癌症死亡比例到 80-84 岁人群中 2.7%的癌症死亡比例。通过以下方式，可能降低由酒精消费引起的癌症负担：（i）降低酒精消费的个人和社会层面的干预措施，和（ii）针对那些与酒精消费相互作用增加癌症风险或直接影响酒精相关癌症风险的因素的措施。