外排泵作为控制耐药菌感染的干预手段。
Efflux pumps as interventions to control infection caused by drug-resistance bacteria.
作者信息
Farhat Nabeela, Ali Abid, Bonomo Robert A, Khan Asad U
机构信息
Medical Microbiology and Molecular Biology Lab, Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, India.
Louis Stokes Cleveland Department of Veteran Affairs Medical Center, Case Western Reserve University, Cleveland, OH, USA.
出版信息
Drug Discov Today. 2020 Dec;25(12):2307-2316. doi: 10.1016/j.drudis.2020.09.028. Epub 2020 Oct 1.
PMID:33011344
Abstract
Antibiotic resistance has become a global concern for healthcare workers and physicians. Efflux pumps are one of the major mechanisms of resistance. Hence, we describe examples of natural efflux pump inhibitors used to combat antibiotic resistance.
摘要
抗生素耐药性已成为医护人员和医生关注的全球性问题。外排泵是主要的耐药机制之一。因此，我们描述了用于对抗抗生素耐药性的天然外排泵抑制剂的实例。
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