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COVID-19 疫苗研发:伦理问题。

COVID-19 vaccine research and development: ethical issues.

机构信息

Department of Microbiology, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.

Medical and Health Research Ethics Committee, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada / Dr. Sardjito General Hospital, Yogyakarta, Indonesia.

出版信息

Trop Med Int Health. 2021 Jan;26(1):14-19. doi: 10.1111/tmi.13503. Epub 2020 Oct 19.

DOI:10.1111/tmi.13503
PMID:33012020
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7675299/
Abstract

The achievements of vaccine research and development bring a hope to our societies that we may cope with the COVID-19 pandemic. There are two aspects that should be maintained in balance: the immediate necessity for speed of vaccine research and the inherent need for protection of research subjects, which is the foremost concern of research ethics. This narrative review highlights ethical issues in COVID-19 vaccine research and development that every stakeholder needs to be aware of and to consider.

摘要

疫苗研发的成果给我们的社会带来了一个希望,即我们可能能够应对 COVID-19 大流行。有两个方面需要保持平衡:疫苗研究的速度的迫切需要和保护研究对象的固有需要,这是研究伦理的首要关注点。本叙述性综述强调了 COVID-19 疫苗研发中每个利益相关者都需要意识到并考虑的伦理问题。

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本文引用的文献

1
Key criteria for the ethical acceptability of COVID-19 human challenge studies: Report of a WHO Working Group.COVID-19 人体挑战研究的伦理可接受性的关键标准:世卫组织工作组的报告。
Vaccine. 2021 Jan 22;39(4):633-640. doi: 10.1016/j.vaccine.2020.10.075. Epub 2020 Oct 28.
2
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques.ChAdOx1 nCoV-19 疫苗可预防恒河猴的 SARS-CoV-2 肺炎。
Nature. 2020 Oct;586(7830):578-582. doi: 10.1038/s41586-020-2608-y. Epub 2020 Jul 30.
3
An mRNA Vaccine against SARS-CoV-2 - Preliminary Report.mRNA 疫苗对 SARS-CoV-2 的作用-初步报告。
N Engl J Med. 2020 Nov 12;383(20):1920-1931. doi: 10.1056/NEJMoa2022483. Epub 2020 Jul 14.
4
Accelerating Development of SARS-CoV-2 Vaccines - The Role for Controlled Human Infection Models.加速严重急性呼吸综合征冠状病毒2(SARS-CoV-2)疫苗的研发——人体感染控制模型的作用
N Engl J Med. 2020 Sep 3;383(10):e63. doi: 10.1056/NEJMp2020076. Epub 2020 Jul 1.
5
Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections.无症状 SARS-CoV-2 感染的临床和免疫学评估。
Nat Med. 2020 Aug;26(8):1200-1204. doi: 10.1038/s41591-020-0965-6. Epub 2020 Jun 18.
6
Current global vaccine and drug efforts against COVID-19: Pros and cons of bypassing animal trials.当前全球针对 COVID-19 的疫苗和药物研发:绕过动物试验的利弊。
J Biosci. 2020;45(1). doi: 10.1007/s12038-020-00053-2.
7
Dengue Fever, COVID-19 (SARS-CoV-2), and Antibody-Dependent Enhancement (ADE): A Perspective.登革热、COVID-19(SARS-CoV-2)和抗体依赖性增强(ADE):一个视角。
Cytometry A. 2020 Jul;97(7):662-667. doi: 10.1002/cyto.a.24047. Epub 2020 Jun 7.
8
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9
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Emerg Microbes Infect. 2020 Dec;9(1):949-961. doi: 10.1080/22221751.2020.1764871.