Margo C E, Mulla Z D
Department of Ophthalmology, University of South Florida, College of Medicine, Tampa, USA.
Ophthalmology. 1998 Jan;105(1):185-90. doi: 10.1016/s0161-6420(98)92107-8.
The purpose of the study is to determine the relative frequency and incidence of primary malignant tumors of the orbit occurring in Florida.
Cases of primary orbital malignancy were identified in the Florida Cancer Data System registry from 1981 through 1993. Analysis was restricted to persons who reside within the state.
Three hundred fourteen primary orbital malignancies were reported; 55% of malignant orbital tumors were lymphoma. The average annual incidence for all malignancies was 2 cases per million. There was a steady increase in the annual incidence of orbital malignancy during the 13 years of the study. Lymphoma showed the greatest rise in annual incidence. The average annual incidence of lymphoma increased 166% the last 6 years of the study compared to the first 6 years.
A large increase in orbital lymphoma was documented in the Florida cancer registry from 1981 through 1993. The increase in incidence cannot be explained by improved compliance in reporting or by the small increase in incidence of systemic lymphoma during the survey period. Additional studies are needed to determine whether the observed increase in incidence in orbital lymphoma is genuine or spurious.
本研究目的在于确定佛罗里达州原发性眼眶恶性肿瘤的相对频率和发病率。
来自1981年至1993年佛罗里达癌症数据系统登记处的原发性眼眶恶性肿瘤病例被纳入研究。分析仅限于居住在该州的人员。
共报告了314例原发性眼眶恶性肿瘤；55%的眼眶恶性肿瘤为淋巴瘤。所有恶性肿瘤的年平均发病率为每百万人口2例。在研究的13年期间，眼眶恶性肿瘤的年发病率呈稳步上升趋势。淋巴瘤的年发病率上升幅度最大。与研究的前6年相比，淋巴瘤在研究的最后6年中年平均发病率增长了166%。
1981年至1993年佛罗里达癌症登记处记录了眼眶淋巴瘤的大幅增加。发病率的增加无法用报告依从性的提高或调查期间系统性淋巴瘤发病率的小幅上升来解释。需要进一步研究以确定观察到的眼眶淋巴瘤发病率增加是真实的还是虚假的。
