Abdelghani Mohamed Salah, Chapra Ammar, Asaad Nidal, Hayat Sajad A
Department of Cardiology, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
Heart Views. 2020 Apr-Jun;21(2):114-117. doi: 10.4103/HEARTVIEWS.HEARTVIEWS_34_20. Epub 2020 Jun 29.
Brugada syndrome (BrS) is a rare genetic disease, of which its clinical manifestations include, but not limited to, syncope or sudden cardiac death. A 30-year-old Bangladeshi male patient with a past medical history of epilepsy was admitted following successful resuscitation from an out of hospital cardiac arrest secondary to ventricular fibrillation. Electrocardiogram (ECG) upon admission was suggestive of BrS type I. His old medical record showed similar ECG 2 months earlier when he had presented with syncope and was diagnosed with seizure. The correlation between BrS and epilepsy has been reported in the literature, discussing whether seizure is an uncommon presentation of BrS or whether epilepsy and BrS share similar genetic mutations that have the potential to cause both arrhythmia and seizures in some patients. Patients who present with seizure and ECG suggestive of Brugada pattern should be evaluated to rule out associated or underlying cardiac arrhythmia.
Brugada综合征（BrS）是一种罕见的遗传性疾病，其临床表现包括但不限于晕厥或心源性猝死。一名30岁的孟加拉男性患者，有癫痫病史，因院外心脏骤停继发室颤成功复苏后入院。入院时心电图（ECG）提示为I型BrS。他的旧病历显示，2个月前他出现晕厥并被诊断为癫痫发作时，心电图与之相似。文献中已报道了BrS与癫痫之间的相关性，探讨癫痫发作是否为BrS的一种不常见表现，或者癫痫和BrS是否共享相似的基因突变，这些基因突变有可能在某些患者中导致心律失常和癫痫发作。出现癫痫发作且心电图提示Brugada图形的患者应进行评估，以排除相关或潜在的心律失常。
