Ozsahin Ilker, Chen Ling, Könik Arda, King Michael A, Beekman Freek J, Mok Greta S P
Biomedical Imaging Laboratory, Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau, China.
Department of Biomedical Engineering, Faculty of Engineering, Near East University, Nicosia/TRNC, Mersin-10, Turkey.
Quant Imaging Med Surg. 2020 Oct;10(10):2006-2029. doi: 10.21037/qims-19-1036.
Single photon emission computed tomography (SPECT) is an important imaging modality for various applications in nuclear medicine. The use of multi-pinhole (MPH) collimators can provide superior resolution-sensitivity trade-off when imaging small field-of-view compared to conventional parallel-hole and fan-beam collimators. Besides the very successful application in small animal imaging, there has been a resurgence of the use of MPH collimators for clinical cardiac and brain studies, as well as other small field-of-view applications. This article reviews the basic principles of MPH collimators and introduces currently available and proposed clinical MPH SPECT systems.
单光子发射计算机断层扫描（SPECT）是核医学中用于各种应用的重要成像方式。与传统的平行孔准直器和扇形束准直器相比，使用多孔径（MPH）准直器在对小视野进行成像时可以提供更好的分辨率-灵敏度权衡。除了在小动物成像中的非常成功的应用外，MPH准直器在临床心脏和脑部研究以及其他小视野应用中的使用也有所复兴。本文回顾了MPH准直器的基本原理，并介绍了目前可用的和提议的临床MPH SPECT系统。
