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骨骼健康与骨质疏松的预防和治疗

Bone Health and Osteoporosis Prevention and Treatment.

机构信息

University of Iowa Carver College of Medicine.

Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.

出版信息

Clin Obstet Gynecol. 2020 Dec;63(4):770-787. doi: 10.1097/GRF.0000000000000572.

Abstract

Postmenopausal osteoporosis is a common condition and is associated with increased risk of fracture, including hip and vertebral fractures that in turn can have devastating consequences on morbidity and mortality. In this article, we review the pathogenesis and diagnostic approach to postmenopausal osteoporosis. We review available nonpharmacologic and pharmacologic therapies and we discuss their clinical efficacy and complications, with a detailed discussion of atypical femur fractures and osteonecrosis of the jaw.

摘要

绝经后骨质疏松症是一种常见病症,与骨折风险增加相关,包括髋部和脊柱骨折,这反过来又会对发病率和死亡率产生严重后果。本文综述了绝经后骨质疏松症的发病机制和诊断方法。我们回顾了现有的非药物和药物治疗方法,并讨论了它们的临床疗效和并发症,详细讨论了非典型股骨骨折和颌骨骨坏死。

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