Centre Hospitalier Le Vinatier, Bron, France; INSERM, U1028; CNRS, UMR5292; Lyon Neuroscience Research Center, Psychiatric Disorders: from Resistance to Response - PSYR2 Team, Lyon F-69000, France; University Lyon 1, Villeurbanne F-69000, France.
Centre Hospitalier Le Vinatier, Bron, France; University Lyon 1, Villeurbanne F-69000, France.
Prev Med. 2020 Dec;141:106264. doi: 10.1016/j.ypmed.2020.106264. Epub 2020 Oct 2.
The current COVID-19 pandemic is the most severe pandemic of the 21st century, on track to having a rising death toll. Beyond causing respiratory distress, COVID-19 may also cause mortality by way of suicide. The pathways by which emerging viral disease outbreaks (EVDOs) and suicide are related are complex and not entirely understood. We aimed to systematically review the evidence on the association between EVDOs and suicidal behaviors and/or ideation. An electronic search was conducted using five databases: Medline, Embase, Web of Science, PsycINFO and Scopus in April 2020. A rapid systematic review was carried out, which involved separately and independently extracting quantitative data of selected articles. The electronic search yielded 2480 articles, of which 9 met the inclusion criteria. Most of the data were collected in Hong Kong (n = 3) and the USA (n = 3). Four studies reported a slight but significant increase in deaths by suicide during EVDOs. The increase in deaths by suicide was mainly reported during the peak epidemic and in older adults. Psychosocial factors such as the fear of being infected by the virus or social isolation related to quarantine measures were the most prominent factors associated with deaths by suicide during EVDOs. Overall, we found scarce and weak evidence for an increased risk of deaths by suicide during EVDOs. Our results inform the need to orient public health policies toward suicide prevention strategies targeting the psychosocial effects of EVDOs. High-quality research on suicide risk and prevention are warranted during the current pandemic.
当前的 COVID-19 大流行是 21 世纪最严重的大流行,死亡人数呈上升趋势。COVID-19 除了引起呼吸窘迫外,还可能通过自杀导致死亡。新兴病毒性疾病暴发(EVDOs)和自杀之间的关联途径复杂,尚未完全理解。我们旨在系统地回顾 EVDOs 与自杀行为和/或意念之间关联的证据。2020 年 4 月,我们使用五个数据库(Medline、Embase、Web of Science、PsycINFO 和 Scopus)进行了电子搜索。我们进行了快速系统评价,其中包括分别和独立地提取选定文章的定量数据。电子搜索共产生了 2480 篇文章,其中 9 篇符合纳入标准。大部分数据是在香港(n=3)和美国(n=3)收集的。四项研究报告称,在 EVDOs 期间,自杀死亡人数略有但显著增加。自杀死亡人数的增加主要发生在疫情高峰期和老年人中。与隔离措施相关的感染病毒的恐惧或社会隔离等心理社会因素是与 EVDOs 期间自杀死亡相关的最突出因素。总体而言,我们发现 EVDOs 期间自杀风险增加的证据很少且很薄弱。我们的研究结果表明,需要将公共卫生政策方向转向针对 EVDOs 心理社会影响的自杀预防策略。在当前大流行期间,有必要进行关于自杀风险和预防的高质量研究。