CV - 1，一种由链霉菌属菌株产生的新型抗生素。I. 抗生素的发酵、分离及生物学特性
CV-1, a new antibiotic produced by a strain of Streptomyces sp. I. Fermentation, isolation and biological properties of the antibiotic.
作者信息
Ichimura M, Koguchi T, Yasuzawa T, Tomita F
出版信息
J Antibiot (Tokyo). 1987 Jun;40(6):723-6. doi: 10.7164/antibiotics.40.723.
PMID:3301772
Abstract
A new antibiotic, CV-1, was isolated from the culture broth of a Streptomyces sp. by various chromatographies. CV-1 showed antibacterial activity against Escherichia coli in cooperation with spiramycin, a macrolide antibiotic. The mode of action of CV-1 seemed to be the inhibition of lipopolysaccharide synthesis.
摘要
一种新的抗生素CV-1，通过各种色谱法从链霉菌属的培养液中分离得到。CV-1与大环内酯类抗生素螺旋霉素协同作用，对大肠杆菌显示出抗菌活性。CV-1的作用方式似乎是抑制脂多糖的合成。
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