斯瓦尔帕霉素，一种新型大环内酯类抗生素。I. 产生菌的分类学、发酵、分离及生物活性
Swalpamycin, a new macrolide antibiotic. I. Taxonomy of the producing organism, fermentation, isolation and biological activity.
作者信息
Franco C M, Gandhi J N, Chatterjee S, Ganguli B N
机构信息
Microbiology Department, Research Centre, Hoechst India Limited, Bombay.
出版信息
J Antibiot (Tokyo). 1987 Oct;40(10):1361-7. doi: 10.7164/antibiotics.40.1361.
PMID:3680001
Abstract
A new macrolide antibiotic, swalpamycin, has been isolated from the culture broth of Streptomyces sp. Y-84,30967. Taxonomically the producing organism most closely resembles Streptomyces anandii and has therefore been named S. anandii subsp. swalpus. Swalpamycin is a neutral 16-membered macrolide active against Gram-positive bacteria including erythromycin-resistant strains.
摘要
一种新的大环内酯类抗生素——斯瓦尔帕霉素，已从链霉菌属菌株Y - 8430967的培养液中分离出来。从分类学角度来看，产生该抗生素的生物体与阿南德链霉菌最为相似，因此被命名为阿南德链霉菌斯瓦尔帕亚种。斯瓦尔帕霉素是一种中性的16元大环内酯类抗生素，对革兰氏阳性菌具有活性，包括耐红霉素菌株。
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