Phan Alex, Joslin Kevin, Truong Phuong, Camp Andrew, Talke Frank E
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:4212-4216. doi: 10.1109/EMBC44109.2020.9175630.
Frequent and accurate monitoring of intraocular pressure is an important aspect of glaucoma management and is central to timely therapeutic intervention and treatment optimization. Intraocular pressure is known to fluctuate not only throughout the day, but also as a function of the heart rate. This pulsatory pressure change behavior is known as the ocular pulse. In this study, we report on the measurement of the ocular pulse profile using a miniaturized intraocular pressure sensor implanted in the eye of a New Zealand White rabbit. The pressure sensor is based on the principle of interferometry and does not require an internal power source. The ocular pulse variation has been measured up to 5 Hz with an accuracy of +/- 0.15 mmHg using both a DSLR reader and a handheld smartphone reader.
频繁且准确地监测眼压是青光眼管理的一个重要方面，对于及时进行治疗干预和优化治疗至关重要。众所周知，眼压不仅会在一天中波动，还会随心率变化。这种搏动性压力变化行为被称为眼脉搏。在本研究中，我们报告了使用植入新西兰白兔眼睛的小型化眼压传感器测量眼脉搏曲线的情况。该压力传感器基于干涉测量原理，无需内部电源。使用数码单反相机读取器和手持式智能手机读取器，已测量出高达5Hz的眼脉搏变化，精度为±0.15mmHg。
