Kaplan R M, Hartwell S L, Wilson D K, Wallace J P
J Gen Intern Med. 1987 Jul-Aug;2(4):220-8. doi: 10.1007/BF02596443.
Evidence suggests that diet and exercise are associated with improved glucose tolerance for patients with non-insulin-dependent diabetes mellitus (NIDDM). Seventy-six volunteer adult patients with NIDDM were each assigned to one of four programs: diet, exercise, diet plus exercise, or education (control). Each program required ten weekly meetings. Detailed evaluations were completed prior to the program and after three, six, 12, and 18 months. Evaluations included various psychosocial measures, measures of the quality of life, and fasting blood glucose, glycosylated hemoglobin, and relative weight determinations. Of the 76 original participants, 70 completed the 18-month follow-up study. At 18 months, the combination diet-and-exercise group had achieved the greatest reductions in glycosylated hemoglobin measures. In addition, this group showed significant improvements on a general quality of life measure. These improvements were largely uncorrelated with changes in weight. The authors conclude that the combination of dietary change and physical conditioning benefits NIDDM patients, and that the benefits may be independent of substantial weight loss.
有证据表明，饮食和运动与非胰岛素依赖型糖尿病（NIDDM）患者糖耐量的改善有关。76名成年NIDDM志愿者患者被分别分配到四个项目之一：饮食、运动、饮食加运动或教育（对照组）。每个项目都需要每周进行十次会面。在项目开始前以及3个月、6个月、12个月和18个月后完成详细评估。评估包括各种心理社会指标、生活质量指标，以及空腹血糖、糖化血红蛋白和相对体重测定。在76名最初的参与者中，70人完成了18个月的随访研究。在18个月时，饮食和运动相结合的组在糖化血红蛋白测量值方面下降幅度最大。此外，该组在一项总体生活质量指标上有显著改善。这些改善在很大程度上与体重变化无关。作者得出结论，饮食改变和身体锻炼相结合对NIDDM患者有益，且这些益处可能独立于显著的体重减轻。
