Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
Department of Pediatric, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
Rev Soc Bras Med Trop. 2020 Oct 5;53:e20190356. doi: 10.1590/0037-8682-0356-2019. eCollection 2020.
This study aimed to evaluate and compare with healthy control subjects the levels of indirect inflammatory markers such as mean platelet volume (MPV), platelet to lymphocyte ratio (PLR), and neutrophil to lymphocyte ratio (NLR) in adults and children with brucellosis.
White blood cell, neutrophil, lymphocyte, and platelet counts, and C-reactive protein (CRP) levels were retrospectively recorded for all participants.
NLR and neutrophil counts were significantly higher in adult patients compared to those in pediatric patients.
Indirect inflammatory markers such as NLR, PLR, MPV, red distribution width, and CRP levels may be helpful for follow-up of brucellosis.
本研究旨在评估并比较成人和儿童布鲁氏菌病患者间接炎症标志物（如平均血小板体积 [MPV]、血小板与淋巴细胞比值 [PLR]和中性粒细胞与淋巴细胞比值 [NLR]）的水平与健康对照组的差异。
对所有参与者的白细胞、中性粒细胞、淋巴细胞和血小板计数以及 C 反应蛋白（CRP）水平进行回顾性记录。
成年患者的 NLR 和中性粒细胞计数显著高于儿科患者。
间接炎症标志物（如 NLR、PLR、MPV、红细胞分布宽度和 CRP 水平）可能有助于布鲁氏菌病的随访。
