Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS S107-5, Atlanta, GA 30341, USA.
Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS S106-7, Atlanta, GA 30341, USA.
Prev Med. 2020 Dec;141:106279. doi: 10.1016/j.ypmed.2020.106279. Epub 2020 Oct 6.
Subjective cognitive decline (SCD) is the self-reported experience of worsening or more frequent confusion or memory loss within the previous 12 months and can be one of the earliest symptoms of Alzheimer's disease. Regular physical activity can contribute to the primary, secondary, and tertiary prevention of cognitive decline. At the national level, prevalence estimates of SCD by physical activity level in the United States are currently unknown. The purpose of this study is to examine the prevalence of SCD and resulting functional limitations by physical activity level among US adults aged ≥45 years. Data from 33 states and the District of Columbia participating in the 2015 Behavioral Risk Factor Surveillance System (N = 128,925) were analyzed. We estimated the prevalence of SCD (a positive response to a question about worsening or more frequent confusion or memory loss within the previous 12 months) and resulting functional limitations overall and by self-reported physical activity level based on current guidelines (i.e., active, insufficiently active, and inactive). Odds ratios were estimated using logistic regression models adjusting for respondent characteristics. Overall, 11.3% of US adults aged ≥45 years reported SCD. Prevalence of SCD increased as physical activity level decreased (active: 8.8%; insufficiently active: 11.4%; inactive: 15.7%). Among those with SCD, the prevalence of functional limitations also increased as physical activity level decreased (active: 40.5%; insufficiently active: 50.0%; inactive: 57.4%). These differences largely remained after adjusting for respondent characteristics. Findings highlight the potential public health impact nationally of efforts to promote physical activity for cognitive health.
主观认知下降（SCD）是指在过去 12 个月内自我报告的认知恶化或记忆丧失更频繁的经历，可能是阿尔茨海默病的最早症状之一。定期进行身体活动有助于认知能力下降的一级、二级和三级预防。在美国，目前尚不清楚按身体活动水平划分的 SCD 患病率的全国估计数。本研究的目的是检查美国≥45 岁成年人中，根据身体活动水平，SCD 的患病率及其导致的功能障碍的情况。分析了来自参与 2015 年行为风险因素监测系统的 33 个州和哥伦比亚特区的数据（N=128925）。我们估计了 SCD 的患病率（对过去 12 个月内认知恶化或记忆丧失更频繁的问题的阳性回答）以及整体和根据当前指南（即积极、活动不足和不活跃）按自我报告的身体活动水平划分的功能障碍的患病率。使用逻辑回归模型调整受访者特征后，估计了比值比。总体而言，11.3%的美国≥45 岁成年人报告了 SCD。SCD 的患病率随着身体活动水平的降低而增加（积极：8.8%；活动不足：11.4%；不活跃：15.7%）。在患有 SCD 的人群中，随着身体活动水平的降低，功能障碍的患病率也增加（积极：40.5%；活动不足：50.0%；不活跃：57.4%）。这些差异在调整受访者特征后基本保持不变。这些发现突出了在全国范围内努力促进身体活动以促进认知健康的潜在公共卫生影响。
