Laakkonen J, Kallio-Kokko H, Oktem M A, Blasdell K, Plyusnina A, Niemimaa J, Karataş A, Plyusnin A, Vaheri A, Henttonen H
Department of Virology, Haartman Institute, University of Helsinki, FIN-00014 Helsinki, Finland.
J Wildl Dis. 2006 Jul;42(3):672-6. doi: 10.7589/0090-3558-42.3.672.
Wild rodents (n = 330) were trapped around the villages of Altindere and Coşandere (Maçka, Trabzon Province), Ayder, Ortan, and Yolkiyi (Camlihemşin, Rize Province), and Bozdag (Odemiş, Izmir Province) in northeastern and western Turkey during April 2004. Samples were tested for arenavirus, hantavirus, and cowpox virus (family Poxviridae, genus Orthopoxvirus, CPXV) antibodies by using immunofluorescence assays (IFAs). Antibodies against arenaviruses were found in eight of 330 (2.4%) rodents. Arenavirus sero-positive animals were found from all study sites. Antibodies to Puumala virus (family Bunyaviridae, genus Hantavirus, PUUV) were detected in four of 65 Microtus voles tested. Of the PUUV-IFA-positive voles, one Microtus guentheri lydius was caught from Izmir, and one Microtus roberti and two Microtus rossiaemeridionalis were captured near Trabzon. All 264 Apodemus spp. mice tested negative for antibodies to Saaremaa virus (family Bunyaviridae, genus Hantavirus, SAAV); the single Dryomys nitedula tested negative for both PUUV and SAAV antibodies. Only one (0.3%) of the rodents, an Apodemus sylvaticus from Trabzon area, tested seropositive to CPXV. This is the first serologic survey for rodent-borne viruses in their natural hosts in Turkey. Although these preliminary results support presence of several virus groups with zoonotic potential, additional studies are needed to identify the specific viruses that are present in these populations.
2004年4月，在土耳其东北部和西部的阿尔廷代雷村和科桑代雷村（特拉布宗省马奇卡）、艾德尔村、奥尔坦村和约尔基伊村（里泽省卡姆利赫姆辛）以及博兹达格村（伊兹密尔省奥代米什）周边捕获了330只野生啮齿动物。通过免疫荧光试验（IFA）对样本进行沙粒病毒、汉坦病毒和牛痘病毒（痘病毒科正痘病毒属，CPXV）抗体检测。在330只啮齿动物中有8只（2.4%）检测出沙粒病毒抗体。在所有研究地点均发现了沙粒病毒血清阳性动物。在检测的65只田鼠中有4只检测出普马拉病毒（布尼亚病毒科汉坦病毒属，PUUV）抗体。在PUUV - IFA阳性的田鼠中，一只古氏田鼠利迪亚种在伊兹密尔捕获，一只罗伯特田鼠和两只南里海田鼠在特拉布宗附近捕获。所有264只姬鼠属小鼠对萨雷马病毒（布尼亚病毒科汉坦病毒属，SAAV）抗体检测均为阴性；唯一一只森林睡鼠对PUUV和SAAV抗体检测均为阴性。只有一只（0.3%）来自特拉布宗地区的林姬鼠对CPXV血清学检测呈阳性。这是土耳其首次对自然宿主中啮齿动物传播病毒进行血清学调查。尽管这些初步结果支持存在几种具有人畜共患病潜力的病毒组，但还需要进一步研究来确定这些种群中存在的具体病毒。
