Department of Tropical Parasitology, Medical University of Gdańsk, Gdańsk, Poland.
Department of Parasitology, University of Warsaw, Warsaw, Poland.
Emerg Microbes Infect. 2018 Aug 15;7(1):145. doi: 10.1038/s41426-018-0149-3.
Rodents are known to play a significant role as reservoir hosts for TBEV. During three sequential expeditions at 4-year intervals to three ecologically similar study sites in NE Poland, we trapped bank voles (Myodes glareolus) and then tested their blood for the presence of specific antiviral antibodies to TBEV. The strongest effects on seroprevalence were the extrinsic factors, site of capture of voles and year of sampling. Seroprevalence increased markedly with increasing host age, and our analysis revealed significant interactions among these three factors. Seroprevalence did not differ between the sexes. Therefore, based on the seroprevalence results, the dynamics of TBEV infection differ significantly in time, between local sub-populations of bank voles and with increasing host age. To fully understand the circulation of the virus among these reservoir hosts and in the environment, long-term monitoring is required and should employ a multi-site approach, such as the one adopted in the current study.
已知啮齿动物在 TBEV 的储存宿主中发挥重要作用。在连续三次为期 4 年的探险中，我们在波兰东北部的三个生态相似的研究地点捕获了林姬鼠（Myodes glareolus），并检测了它们血液中是否存在针对 TBEV 的特定抗病毒抗体。对血清阳性率影响最大的是外在因素，即捕获田鼠的地点和采样年份。血清阳性率随宿主年龄的增加而显著增加，我们的分析显示这三个因素之间存在显著的相互作用。性别之间的血清阳性率没有差异。因此，根据血清阳性率的结果，TBEV 感染的动力学在时间上、在林姬鼠的局部亚种群之间以及随着宿主年龄的增加而显著不同。为了充分了解病毒在这些储存宿主和环境中的传播，需要进行长期监测，并应采用多地点的方法，如本研究中采用的方法。
