Cleveland Clinic Akron General, Department of Emergency Medicine, Akron, OH, United States of America; Northeast Ohio Medical University, Rootstown, OH, United States of America.
Cleveland Clinic Akron General, Department of Emergency Medicine, Akron, OH, United States of America; Northeast Ohio Medical University, Rootstown, OH, United States of America.
Am J Emerg Med. 2021 Jul;45:154-155. doi: 10.1016/j.ajem.2020.07.074. Epub 2020 Aug 4.
As the COVID-19 pandemic continues to progress, the medical community is rapidly trying to identify complications and patterns of disease to improve patient outcomes. In a recent systematic review, it has been reported that isolated cases of Guillain-Barre Syndrome (GBS) have occurred secondary to COVID-19 infection. GBS is defined as a rare, but potentially fatal, immune mediated disease of peripheral nerves and nerve roots that is usually triggered by infections. The incidence of GBS can therefore increase during outbreaks of infectious diseases, as was seen during the Zika virus epidemics in 2013 in French Polynesia and 2015 in Latin America. While several cases of GBS secondary to COVID-19 infection have been reported in Italy, only one case has been reported in the United States (US). The reported case in the US was a 54- year old male. We present a case of GBS secondary to a COVID-19 infection and believe this to be the first documented female case in the US and the second documented case in the US overall. The presented case aims to supplement the existing body of knowledge and to assist clinicians in managing complications of COVID-19.
随着 COVID-19 大流行的持续发展,医学界正在迅速努力识别疾病的并发症和模式,以改善患者的预后。在最近的一项系统评价中,据报道 COVID-19 感染后会发生孤立的吉兰-巴雷综合征(GBS)病例。GBS 被定义为一种罕见但潜在致命的免疫介导性周围神经和神经根疾病,通常由感染引发。因此,传染病爆发期间 GBS 的发病率会增加,正如 2013 年在法属波利尼西亚和 2015 年在拉丁美洲的寨卡病毒流行期间所看到的那样。虽然意大利已经报告了几例与 COVID-19 感染相关的 GBS 病例,但在美国仅报告了一例。美国报告的病例是一名 54 岁男性。我们报告了一例继发于 COVID-19 感染的 GBS 病例,我们认为这是美国首例有记录的女性病例,也是美国的第二例有记录的病例。该病例旨在补充现有知识体系,并帮助临床医生管理 COVID-19 的并发症。