firA基因的精细结构图谱，该基因座参与大肠杆菌中利福平抗性的表型表达。
Fine-structure mapping of the firA gene, a locus involved in the phenotypic expression of rifampin resistance in Escherichia.
作者信息
Lathe R
出版信息
J Bacteriol. 1977 Sep;131(3):1033-6. doi: 10.1128/jb.131.3.1033-1036.1977.
Abstract
The firA (Ts)200 mutation not only eliminates the resistance to rifampin of certain genetically resistant strains, but, moreover, renders ribonucleic acid synthesis thermolabile. The firA gene has been mapped by P1 tranduction and is located extremely close to the structural gene for deoxyribonucleic acid polymerase III at 4 min on the Escherichia coli linkage map.
摘要
firA（Ts）200突变不仅消除了某些遗传抗性菌株对利福平的抗性，而且使核糖核酸合成对温度敏感。firA基因已通过P1转导进行定位，位于大肠杆菌连锁图谱上4分钟处，与脱氧核糖核酸聚合酶III的结构基因极为接近。
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