Triggiano Francesco, Calia Carla, Diella Giusy, Montagna Maria Teresa, De Giglio Osvalda, Caggiano Giuseppina
Department of Biomedical Science and Human Oncology, University of Bari Aldo Moro, Piazza G. Cesare 11, 70124 Bari, Italy.
Microorganisms. 2020 Oct 12;8(10):1567. doi: 10.3390/microorganisms8101567.
Scientific studies show that urban wastewater treatment plants (UWWTP) are among the main sources of release of antibiotics, antibiotic resistance genes (ARG) and antibiotic-resistant bacteria (ARB) into the environment, representing a risk to human health. This review summarizes selected publications from 1 January 2010 to 31 December 2019, with particular attention to the presence and treatment of ARG and ARB in UWWTPs in Italy. Following a brief introduction, the review is divided into three sections: (i) phenotypic assessment (ARB) and (ii) genotypic assessment (ARG) of resistant microorganisms, and (iii) wastewater treatment processes. Each article was read entirely to extract the year of publication, the geographical area of the UWWTP, the ARB and ARG found, and the type of disinfection treatment used. Among the ARB, we focused on the antibiotic resistance of , , and Enterococci in UWWTP. The results show that the information presented in the literature to date is not exhaustive; therefore, future scientific studies at the national level are needed to better understand the spread of ARB and ARG, and also to develop new treatment methods to reduce this spread.
科学研究表明，城市污水处理厂是抗生素、抗生素抗性基因（ARG）和抗生素抗性细菌（ARB）向环境中释放的主要来源之一，对人类健康构成风险。本综述总结了2010年1月1日至2019年12月31日期间的部分出版物，特别关注意大利城市污水处理厂中ARG和ARB的存在及处理情况。在简要介绍之后，综述分为三个部分：（i）抗性微生物的表型评估（ARB）和（ii）基因型评估（ARG），以及（iii）废水处理工艺。每篇文章都被通读，以提取出版年份、城市污水处理厂的地理区域、发现的ARB和ARG以及使用的消毒处理类型。在ARB中，我们重点关注城市污水处理厂中大肠埃希菌、金黄色葡萄球菌和肠球菌的抗生素抗性。结果表明，迄今为止文献中提供的信息并不详尽；因此，需要在国家层面开展未来的科学研究，以更好地了解ARB和ARG的传播情况，并开发新的处理方法来减少这种传播。
