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雾霭、诱惑与成瘾:雾化吸入的肺部效应及其主要液体成分的作用

The fog, the attractive and the addictive: pulmonary effects of vaping with a focus on the contribution of each major vaping liquid constituent.

机构信息

Quebec Heart and Lung Institute, Université Laval, Quebec, Canada.

Faculty of Medicine, Université Laval, Quebec, Canada.

出版信息

Eur Respir Rev. 2020 Oct 15;29(157). doi: 10.1183/16000617.0268-2020. Print 2020 Sep 30.

Abstract

Vaping has become increasingly popular over the past decade. This pragmatic review presents the published biological effects of electronic cigarette vapour inhalation with a focus on the pulmonary effects. Special attention has been devoted to providing the documented effects specific to each major ingredient, namely propylene glycol/glycerol, nicotine and flavouring agents. For each ingredient, findings are divided according to the methodology used, being studies, animal studies and clinical studies. Finally, we provide thoughts and insights on the current state of understanding of the pulmonary effects of vaping, as well as novel research avenues and methodologies.

摘要

在过去的十年中,蒸气吸入(vaping)变得越来越流行。本实践综述介绍了已发表的电子香烟蒸气吸入的生物学效应,重点是肺部效应。特别注意提供了针对每个主要成分(即丙二醇/甘油、尼古丁和调味剂)的有文件记录的特定影响。对于每个成分,根据所使用的方法将研究结果进行了划分,即研究、动物研究和临床研究。最后,我们对目前对蒸气吸入肺部效应的理解状况,以及新的研究途径和方法,提供了一些思考和见解。

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