Van Nuffel Stefaan, Claeys Matthias F, Claeys Marnix H
Department of Ophthalmology, University Hospital Ghent, Ghent, Belgium.
Okulus Eye Clinic, Kortrijk, Belgium.
Clin Ophthalmol. 2020 Sep 25;14:2873-2878. doi: 10.2147/OPTH.S261565. eCollection 2020.
To compare postoperative changes in central subfield macular thickness (CSMT) and prevalence of cystoid macular edema (CME) in patients undergoing cataract surgery with low-energy femtosecond laser versus standard phacoemulsification.
This was a retrospective comparative real-world study.
Postoperative data of 252 eyes of 165 patients were collected: 138 eyes received low-energy femtosecond laser-assisted cataract surgery (FLACS) and 114 eyes underwent conventional phacoemulsification cataract surgery (CPCS). Postoperative changes in CSMT and prevalence of CME were compared between the two groups.
There was a significant increase in mean CSMT from preoperative to postoperative values at 2.5 months in both the FLACS and CPCS group (<0.001). Mean change (preoperation to 2.5 months postoperation) in CSMT was 6.2±11.5 µm in the FLACS group and 7.3±26.6 µm in the CPCS group, which was statistically significant but clinically not relevant. Comparison of mean changes in CSMT (preoperation to 2.5 months postoperation) between the FLACS and CPCS groups revealed no significant differences. The rate of pseudophakic CME (PCME) development was lower in the FLACS group (1.4%) than the CPCS group (4.4%; =0.247). When using PREMED criteria to define clinically significant PCME, only 0.7% patients in the FLACS group and 1.8% in the CPCS group showed development of clinically significant PCME (=0.586).
The mean change in CSMT and occurrence of postoperative CME was lower in the low-energy FLACS group than the standard-phacoemulsification group; however, the difference was not statistically significant.
比较接受低能量飞秒激光白内障手术与标准超声乳化白内障手术患者的黄斑中心子区域厚度（CSMT）术后变化及黄斑囊样水肿（CME）的发生率。
这是一项回顾性比较真实世界研究。
收集了165例患者252只眼的术后数据：138只眼接受了低能量飞秒激光辅助白内障手术（FLACS），114只眼接受了传统超声乳化白内障手术（CPCS）。比较两组CSMT的术后变化及CME的发生率。
FLACS组和CPCS组在术后2.5个月时，平均CSMT从术前到术后值均有显著增加（<0.001）。FLACS组CSMT的平均变化（术前至术后2.5个月）为6.2±11.5 µm，CPCS组为7.3±26.6 µm，差异有统计学意义但临床意义不大。FLACS组和CPCS组之间CSMT的平均变化（术前至术后2.5个月）比较无显著差异。FLACS组人工晶状体眼CME（PCME）的发生率（1.4%）低于CPCS组（4.4%；P = 0.247）。当使用PREMED标准定义具有临床意义的PCME时，FLACS组仅0.7%的患者和CPCS组1.8%的患者出现具有临床意义的PCME（P = 0.586）。
低能量FLACS组CSMT的平均变化及术后CME的发生率低于标准超声乳化组；然而，差异无统计学意义。
