Radiology Department, Istanbul University, Istanbul Medical Faculty, Fatih, Millet Street, 34390, Istanbul, Turkey.
Radiology Department, Istanbul University, Istanbul Medical Faculty, Fatih, Millet Street, 34390, Istanbul, Turkey.
Acad Radiol. 2021 Jan;28(1):18-27. doi: 10.1016/j.acra.2020.10.002. Epub 2020 Oct 5.
This study aims to reveal the imaging features of Coronavirus Disease 2019 (COVID-19) in children.
Sixty-nine chest radiographs and 37 chest CT examinations of 74 children (36 male; median (interquartile range) age:11 (6.25-15) years, 38 female; median (interquartile range) age: 12 (5.75-16) years) with positive real-time reverse transcription-polymerase chain reaction results between March 10 and May 31, 2020, were evaluated in this retrospective study. Differences in 0-<6, 6-<12, and 12-18 years of age groups were assessed with the Fisher's exact test or Kruskal-Wallis tests.
Right-sided (3/69, 4.3%) or bilateral (3/69, 4.3%) ground-glass opacities without significant difference in age groups were depicted as radiographic findings related to COVID-19 in children. Opacities were either single (7/37, 18.9%) or bilateral (7/37, 18.9%) around the distal third of the bronchovascular bundle on CT. There was no significant difference in the median size of the largest opacities, total numbers of opacities and involved lobes, and the distance of the closest opacity to the pleura among age groups (p > 0.05). The rate of ground-glass opacities with or without consolidation (17/37, 45.94%) was higher than consolidation alone (6/37, 16.2%). Feeding vessel sign (16/37, 43.2%), halo sign (9/37, 24.3%), pleural thickening (6/37, 16.2%), interlobular interstitial thickening (5/37, 13.5%), and lymphadenopathy (3/37, 8.1%) were other imaging findings.
Unilateral or bilateral distributed ground-glass opacities often associated with feeding vessel sign, halo sign, and pleural thickening on chest CT without significant differences between age groups were findings of COVID-19 in children.
本研究旨在揭示儿童 2019 年冠状病毒病（COVID-19）的影像学特征。
本回顾性研究纳入了 2020 年 3 月 10 日至 5 月 31 日期间经实时逆转录-聚合酶链反应检测结果为阳性的 74 例儿童（男 36 例，中位（四分位间距）年龄：11（6.25-15）岁；女 38 例，中位（四分位间距）年龄：12（5.75-16）岁）的 69 份胸部 X 线片和 37 份胸部 CT 检查结果。采用 Fisher 确切检验或 Kruskal-Wallis 检验评估 0-<6、6-<12 和 12-18 岁年龄组之间的差异。
右肺（3/69，4.3%）或双肺（3/69，4.3%）磨玻璃影，各组间年龄无显著差异，为儿童 COVID-19 的放射学表现。CT 上，磨玻璃影呈单侧（7/37，18.9%）或双侧（7/37，18.9%）分布，位于支气管血管束远端三分之一处。各组间最大磨玻璃影的中位数大小、磨玻璃影总数、受累肺叶数以及最接近胸膜的磨玻璃影距离无显著差异（p>0.05）。磨玻璃影伴或不伴实变（17/37，45.94%）的发生率高于单纯实变（6/37，16.2%）。CT 上还可见滋养血管征（16/37，43.2%）、晕征（9/37，24.3%）、胸膜增厚（6/37，16.2%）、小叶间隔增厚（5/37，13.5%）和淋巴结肿大（3/37，8.1%）。
胸部 CT 上无明显年龄差异的单侧或双侧分布的磨玻璃影常伴有滋养血管征、晕征和胸膜增厚，是儿童 COVID-19 的影像学表现。
