Department of Psychiatry, Devdaha Medical College, Rupandehi, Nepal.
Department of Biochemistry, Devdaha Medical College, Rupandehi, Nepal.
JNMA J Nepal Med Assoc. 2020 Sep 27;58(229):654-658. doi: 10.31729/jnma.5296.
Patients with thyroid disorders are more prone to develop depressive symptoms and conversely depression may be accompanied by various subtle thyroid abnormalities. The aim of the study was to estimate the prevalence of thyroid dysfunction in depression.
This is a descriptive cross-sectional study conducted at Devdaha Medical College and Research Institute employing a simple random sampling technique during the period of August 2019-January 2020. The research was approved by the Ethical Committee of the Institutional Review Board of Devdaha Medical College and Research Institute. The protocol approval number is 009/019. Data analysis was done in Statistical Package for the Social Sciences (Version 23). Results were presented as frequencies and percentages where required.
Among 263 patients with depression, 69 (26.2%) had abnormal thyroid status with most common being subclinical hypothyroidism 32 (12.2%), 13 (4.9%) overt hypothyroidism and 7 (2.7%) overt hyperthyroidism.
The prevalence of thyroid dysfunction is high among patients with depression. We recommend to conduct routine thyroid function tests for all the patients with depression.
甲状腺疾病患者更容易出现抑郁症状,反之,抑郁可能伴有各种微妙的甲状腺异常。本研究旨在评估甲状腺功能障碍在抑郁症中的患病率。
这是一项描述性横断面研究,于 2019 年 8 月至 2020 年 1 月期间在 Devdaha 医学院和研究所进行,采用简单随机抽样技术。该研究得到了 Devdaha 医学院和研究所机构审查委员会伦理委员会的批准。方案批准编号为 009/019。数据分析使用社会科学统计软件包(版本 23)进行。结果以频率和百分比表示。
在 263 例抑郁症患者中,69 例(26.2%)甲状腺功能异常,最常见的是亚临床甲状腺功能减退症 32 例(12.2%)、临床甲状腺功能减退症 13 例(4.9%)和临床甲状腺功能亢进症 7 例(2.7%)。
抑郁症患者中甲状腺功能障碍的患病率很高。我们建议对所有抑郁症患者进行常规甲状腺功能检查。