Nie Anzheng, Chao Yanhui, Zhang Xiaochuan, Jia Wenrui, Zhou Zheng, Zhu Chunsheng
Department of Chinese Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Front Pharmacol. 2020 Sep 15;11:505249. doi: 10.3389/fphar.2020.505249. eCollection 2020.
is the dried sclerotium of (F.A. Wolf) Ryvarden & Gilb., which was the current accepted name and was formerly known as (Schwein.) I. Johans. & Ryvarden, (Schwein.) Fr., F.A. Wolf and Schwein. It is one of the most important crude drugs in traditional Chinese medicine, with a wide range of applications in ameliorating phlegm and edema, relieving nephrosis and chronic gastritis and improving uneasiness of minds. Its extensive pharmacological effects have attracted considerable attention in recent years. However, there is no systematic review focusing on the chemical compounds and pharmacological activities of . Therefore, this review aimed to provide the latest information on the chemical compounds and pharmacological effects of , exploring the therapeutic potential of these compounds. We obtained the information of from electronic databases such as SCI finder, PubMed, Web of Science, CNKI, WanFang DATA and Google Scholar. Up to now, two main active ingredients, triterpenes and polysaccharides of , have been identified from . It has been reported that they have pharmacological effects on anti-tumor, anti-bacterial, anti-oxidant, anti-inflammatory, immunomodulation, and liver and kidney protection. The review summarizes the phytochemistry and pharmacological properties of , which suggest that researchers should focus on the development of new drugs about to make them exert greater therapeutic potential.
是茯苓（F.A. Wolf）Ryvarden & Gilb. 的干燥菌核，这是当前被认可的名称，其曾被称为茯苓（Schwein.）I. Johans. & Ryvarden、茯苓（Schwein.）Fr.、茯苓F.A. Wolf和茯苓Schwein.。它是传统中药中最重要的药材之一，在化痰、利水、缓解肾病和慢性胃炎以及改善心神不安方面有广泛应用。其广泛的药理作用近年来引起了相当大的关注。然而，目前尚无针对茯苓的化学成分和药理活性的系统综述。因此，本综述旨在提供茯苓化学成分和药理作用的最新信息，探索这些化合物的治疗潜力。我们从SCI finder、PubMed、Web of Science、CNKI、万方数据和谷歌学术等电子数据库中获取茯苓的相关信息。截至目前，已从茯苓中鉴定出两种主要活性成分，即三萜类化合物和多糖。据报道，它们具有抗肿瘤、抗菌、抗氧化、抗炎、免疫调节以及肝肾保护等药理作用。本综述总结了茯苓的植物化学和药理特性，表明研究人员应关注茯苓新药的开发，以使它们发挥更大的治疗潜力。
