Dionigi Gianlorenzo, Fama' Fausto, Pignata Salvatore Antonio, Pino Antonella, Pontin Alessandro, Caruso Ettore, Fu Yantao, Li Shijie, Mazzeo Carmelo, Sun Hui, Baldari Sergio
Division for Endocrine and Minimally Invasive Surgery, Department of Human Pathology in Adulthood and Childhood "G. Barresi'', University Hospital G. Martino, University of Messina, Messina, Italy.
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University Hospital G. Martino, University of Messina, Messina, Italy.
World J Otorhinolaryngol Head Neck Surg. 2020 Jul 7;6(3):182-187. doi: 10.1016/j.wjorl.2020.02.008. eCollection 2020 Sep.
The aim of this paper is to discuss the risk of recurrence in patients with differentiated thyroid cancer and emphasize the importance of risk-group stratification, early recurrence identification and application of new imaging modalities, what is the PET-CT. Moreover, follow-up of patients with thyroid carcinoma should be carried out by specialized teams throughout life. Therefore, interdisciplinary case discussions in tumor conferences may improve the use of multimodal therapy especially in patients with poorly differentiated thyroid carcinomas. After baseline follow-up, if there is a suspicion of thyroid carcinoma, early PET-CT should be used for early detection and appropriate planning. Fortunately, due to the good localization possibility, the PET-CT enables a focused surgical procedure with avoidance of an unnecessary tumor search and thereby a reduction of the risk of injury of neighboring structures which is a concern with reoperative neck surgery.
本文旨在探讨分化型甲状腺癌患者的复发风险，并强调风险分组分层、早期复发识别以及新型成像模式（即PET-CT）应用的重要性。此外，甲状腺癌患者应终身由专业团队进行随访。因此，在肿瘤会议上进行多学科病例讨论可能会改善多模式治疗的应用，尤其是对于低分化甲状腺癌患者。在基线随访后，如果怀疑患有甲状腺癌，应尽早使用PET-CT进行早期检测和适当的治疗规划。幸运的是，由于PET-CT具有良好的定位可能性，它能够实现精准的手术操作，避免不必要的肿瘤探查，从而降低再次颈部手术时邻近结构损伤风险，而这种风险在再次颈部手术中是需要关注的问题。
